Quinapril verso lisinopril nel trattamento dell'ipertensione essenziale in pazienti anziani con bassa reninemia

Translated title of the contribution: Quinapril versus lisinopril in the treatment of essential hypertension in old patients with low levels of plasmarenin

F. Rengo, V. Canonico

Research output: Contribution to journalArticle

Abstract

The aim of the study was to evaluate efficacy and tolerability of quinapril 20 mg once-a-day versus lisinopril 20 mg, in the treatment of old patients suffering from essential mild or moderate hypertension and presenting low levels of plasmarenin. It was a crossover study with open treatments randomly assigned. Ten patiens were treated, 6 females and 4 males, with average age of 67.1 years ± 7.1. Two wash-out periods with placebo were scheduled, each lasting one week before the onset of active therapy; each treatment period lasted 21 days. Blood pressure controls (including the 24 hours monitoring) were done at basal time, after seven days and at the end of each treatment. Results show the efficacy and the safety of both the drugs and a more effective and constant control of hypertension by Quinapril was confirmed.

Original languageItalian
Pages (from-to)631-635
Number of pages5
JournalMinerva Cardioangiologica
Volume44
Issue number12
Publication statusPublished - 1996

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ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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