R Engine Cell: Integrating R into the i2b2 software infrastructure

Daniele Segagni, Fulvia Ferrazzi, Cristiana Larizza, Valentina Tibollo, Carlo Napolitano, Silvia G. Priori, Riccardo Bellazzi

Research output: Contribution to journalArticlepeer-review


Informatics for Integrating Biology and the Bedside (i2b2) is an initiative funded by the NIH that aims at building an informatics infrastructure to support biomedical research. The University of Pavia has recently integrated i2b2 infrastructure with a registry of inherited arrhythmogenic diseases. Within this project, the authors created a novel i2b2 cell, named R Engine Cell, which allows the communication between i2b2 and the R statistical software. As survival analyses are routinely performed by cardiology researchers, the authors have first concentrated on making KaplaneMeier analyses available within the i2b2 web interface. To this aim, the authors developed a web-client plug-in to select the patient set on which to perform the analysis and to display the results in a graphical, intuitive way. R Engine Cell has been designed to easily support the integration of other R-based statistical analyses into i2b2.

Original languageEnglish
Pages (from-to)314-317
Number of pages4
JournalJournal of the American Medical Informatics Association
Issue number3
Publication statusPublished - May 2011

ASJC Scopus subject areas

  • Health Informatics


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