Abstract
Radiation-induced sarcomas are rare, high-grade sarcomas that may arise within the radiation volume at a mean latency period of 3-55 years after radiation therapy, doses of which range from 45 to 60 Gy. Radiation-induced osteosarcomas, fibrosarcomas, and malignant fibrous histiocytomas are the most common. Extensive surgery with microscopically negative-margin resection, or amputation is recommended for improved survival. Adjuvant radiation therapy and chemotherapy have not been shown to improve survival rates significantly. The prognosis is poor.
Original language | English |
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Pages (from-to) | 233-240 |
Number of pages | 8 |
Journal | Journal of Long-Term Effects of Medical Implants |
Volume | 21 |
Issue number | 3 |
Publication status | Published - 2011 |
Keywords
- Bone sarcomas
- Radiation therapy
- Soft-tissue sarcomas
ASJC Scopus subject areas
- Biomedical Engineering
- Dentistry(all)