Radiation therapy vs radiation therapy + pamidronate (Aredia®) in elderly patients with breast cancer and lytic bone metastases: A GROG-GIOGer randomized clinical trial

G. Ausili-Cefaro, C. Capirci, D. Crivellari, V. Fontana, G. Mandoliti, P. Olmi, G. Pavanato, C. Polico, G. Porcile, L. Repetto, A. Venturino

Research output: Contribution to journalArticle

Abstract

The contribution of diphosphonate treatment to pain control and consolidation of breast cancer bone metastases, especially referred to older patients aged > 70 was analyzed. In particular, a randomized clinical trial was planned to compare the standard radiation therapy as sole treatment versus radiation therapy combined with pamidronate administration. Consumption of analgesics was considered as evaluation parameter of treatment effectiveness. Toxicity and quality of life with both treatment schedules were evaluated.

Original languageEnglish
Pages (from-to)49-52
Number of pages4
JournalRays - International Journal of Radiological Sciences
Volume24
Issue number2 SUPPL.
Publication statusPublished - 1999

Keywords

  • Bone metastases
  • Elderly
  • Pamidronate
  • Radiotherapy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Ausili-Cefaro, G., Capirci, C., Crivellari, D., Fontana, V., Mandoliti, G., Olmi, P., Pavanato, G., Polico, C., Porcile, G., Repetto, L., & Venturino, A. (1999). Radiation therapy vs radiation therapy + pamidronate (Aredia®) in elderly patients with breast cancer and lytic bone metastases: A GROG-GIOGer randomized clinical trial. Rays - International Journal of Radiological Sciences, 24(2 SUPPL.), 49-52.