Radio-chemotherapy of anal cancer

Roberto Zucali, Roberto Doci, Rado Kenda, Laura Lozza, Silvia Tana, Francesca Valvo

Research output: Contribution to journalArticle

Abstract

Conventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotheraphy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80% of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
JournalTumori
Volume84
Issue number2
Publication statusPublished - Mar 1998

Fingerprint

Anus Neoplasms
Radio
Drug Therapy
Mitomycin
Fluorouracil
Radiotherapy
Therapeutics
Neoplasms

Keywords

  • Anal cancer
  • Radio-chemotherapy

ASJC Scopus subject areas

  • Cancer Research

Cite this

Zucali, R., Doci, R., Kenda, R., Lozza, L., Tana, S., & Valvo, F. (1998). Radio-chemotherapy of anal cancer. Tumori, 84(2), 247-249.

Radio-chemotherapy of anal cancer. / Zucali, Roberto; Doci, Roberto; Kenda, Rado; Lozza, Laura; Tana, Silvia; Valvo, Francesca.

In: Tumori, Vol. 84, No. 2, 03.1998, p. 247-249.

Research output: Contribution to journalArticle

Zucali, R, Doci, R, Kenda, R, Lozza, L, Tana, S & Valvo, F 1998, 'Radio-chemotherapy of anal cancer', Tumori, vol. 84, no. 2, pp. 247-249.
Zucali R, Doci R, Kenda R, Lozza L, Tana S, Valvo F. Radio-chemotherapy of anal cancer. Tumori. 1998 Mar;84(2):247-249.
Zucali, Roberto ; Doci, Roberto ; Kenda, Rado ; Lozza, Laura ; Tana, Silvia ; Valvo, Francesca. / Radio-chemotherapy of anal cancer. In: Tumori. 1998 ; Vol. 84, No. 2. pp. 247-249.
@article{909da37ee5e14ce499f368f58daf4130,
title = "Radio-chemotherapy of anal cancer",
abstract = "Conventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotheraphy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80{\%} of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.",
keywords = "Anal cancer, Radio-chemotherapy",
author = "Roberto Zucali and Roberto Doci and Rado Kenda and Laura Lozza and Silvia Tana and Francesca Valvo",
year = "1998",
month = "3",
language = "English",
volume = "84",
pages = "247--249",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "2",

}

TY - JOUR

T1 - Radio-chemotherapy of anal cancer

AU - Zucali, Roberto

AU - Doci, Roberto

AU - Kenda, Rado

AU - Lozza, Laura

AU - Tana, Silvia

AU - Valvo, Francesca

PY - 1998/3

Y1 - 1998/3

N2 - Conventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotheraphy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80% of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.

AB - Conventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotheraphy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80% of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.

KW - Anal cancer

KW - Radio-chemotherapy

UR - http://www.scopus.com/inward/record.url?scp=0031748705&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031748705&partnerID=8YFLogxK

M3 - Article

C2 - 9620252

AN - SCOPUS:0031748705

VL - 84

SP - 247

EP - 249

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 2

ER -