Radio-chemotherapy of anal cancer

Roberto Zucali, Roberto Doci, Rado Kenda, Laura Lozza, Silvia Tana, Francesca Valvo

Research output: Contribution to journalArticlepeer-review


Conventional treatment of anal cancer has been the demolitive Miles operation for decades. Radiotherapy has been utilized in a limited number of centers for early cancers only. Radio-chemotheraphy has become the treatment of choice for all stages of anal cancer after the first experiences by the group of Detroit and after the confirmation of successful results by many other centers. Infusional chemotherapy (5-FU and Mitomycin C or CDDP) and concurrent irradiation are able to achieve local control in more than 80% of patients. Surgery currently represents a rescue treatment for partial responders or in relapsing patients. A brief review of the literature and the experience at the Istituto Tumori in Milano are presented.

Original languageEnglish
Pages (from-to)247-249
Number of pages3
Issue number2
Publication statusPublished - Mar 1998


  • Anal cancer
  • Radio-chemotherapy

ASJC Scopus subject areas

  • Cancer Research


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