TY - JOUR
T1 - Radio-induced gliomas
T2 - 20-year experience and critical review of the pathology
AU - Salvati, Maurizio
AU - D'Elia, Alessandro
AU - Melone, Graziella Angelina
AU - Brogna, Christian
AU - Frati, Alessandro
AU - Raco, Antonino
AU - Delfini, Roberto
PY - 2008
Y1 - 2008
N2 - The authors report their personal experience with a surgical series of 16 cases of cerebral radiation-induced gliomas, defining diagnostic criteria and surgical and clinical characteristics. There were ten males and six females, with a median age of 45.9 years. Irradiation had initially been given for acute lymphoblastic leukemia (ALL) in six cases, tinea capitis in four cases, scalp hemangioma in three cases, cutaneous hemangioma, cavernous angioma, and medulloblastoma in one case each. There were 14 cases of glioblastoma (grade IV WHO) and 2 cases of astrocytoma (grade II WHO), with a mean latency time of 17 years (range: 6-26 years). For glioblastomas mean survival time was 10.4 months, accounting for 1-3% of all the glioblastomas treated. A thorough revision of the pertinent literature revealed some clinical-biological peculiarities.
AB - The authors report their personal experience with a surgical series of 16 cases of cerebral radiation-induced gliomas, defining diagnostic criteria and surgical and clinical characteristics. There were ten males and six females, with a median age of 45.9 years. Irradiation had initially been given for acute lymphoblastic leukemia (ALL) in six cases, tinea capitis in four cases, scalp hemangioma in three cases, cutaneous hemangioma, cavernous angioma, and medulloblastoma in one case each. There were 14 cases of glioblastoma (grade IV WHO) and 2 cases of astrocytoma (grade II WHO), with a mean latency time of 17 years (range: 6-26 years). For glioblastomas mean survival time was 10.4 months, accounting for 1-3% of all the glioblastomas treated. A thorough revision of the pertinent literature revealed some clinical-biological peculiarities.
KW - High grade
KW - Low grade
KW - Radiation-induced gliomas
KW - Radiosurgery
KW - Radiotherapy
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U2 - 10.1007/s11060-008-9565-x
DO - 10.1007/s11060-008-9565-x
M3 - Article
C2 - 18566750
AN - SCOPUS:48749133262
VL - 89
SP - 169
EP - 177
JO - Journal of Neuro-Oncology
JF - Journal of Neuro-Oncology
SN - 0167-594X
IS - 2
ER -