Radio-induced low-grade glioma: Report of two cases and review of the literature

Alessandro D'Elia, Graziella Angelina Melone, Christian Brogna, Anna Formichella, Antonio Santoro, Maurizio Salvati

Research output: Contribution to journalArticle

Abstract

With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalNeurological Sciences
Volume30
Issue number2
DOIs
Publication statusPublished - 2009

Keywords

  • Low-grade glioma
  • Radiation-induced glioma
  • Radiotherapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology

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    D'Elia, A., Melone, G. A., Brogna, C., Formichella, A., Santoro, A., & Salvati, M. (2009). Radio-induced low-grade glioma: Report of two cases and review of the literature. Neurological Sciences, 30(2), 137-141. https://doi.org/10.1007/s10072-009-0017-y