Radio-induced low-grade glioma: Report of two cases and review of the literature

Alessandro D'Elia, Graziella Angelina Melone, Christian Brogna, Anna Formichella, Antonio Santoro, Maurizio Salvati

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalNeurological Sciences
Volume30
Issue number2
DOIs
Publication statusPublished - 2009

Fingerprint

Radio
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Glioma
Cranial Irradiation
Adjuvant Radiotherapy
Brain Neoplasms
Survivors
Neoplasms
Radiotherapy
Radiation
Population

Keywords

  • Low-grade glioma
  • Radiation-induced glioma
  • Radiotherapy

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology

Cite this

D'Elia, A., Melone, G. A., Brogna, C., Formichella, A., Santoro, A., & Salvati, M. (2009). Radio-induced low-grade glioma: Report of two cases and review of the literature. Neurological Sciences, 30(2), 137-141. https://doi.org/10.1007/s10072-009-0017-y

Radio-induced low-grade glioma : Report of two cases and review of the literature. / D'Elia, Alessandro; Melone, Graziella Angelina; Brogna, Christian; Formichella, Anna; Santoro, Antonio; Salvati, Maurizio.

In: Neurological Sciences, Vol. 30, No. 2, 2009, p. 137-141.

Research output: Contribution to journalArticle

D'Elia, A, Melone, GA, Brogna, C, Formichella, A, Santoro, A & Salvati, M 2009, 'Radio-induced low-grade glioma: Report of two cases and review of the literature', Neurological Sciences, vol. 30, no. 2, pp. 137-141. https://doi.org/10.1007/s10072-009-0017-y
D'Elia, Alessandro ; Melone, Graziella Angelina ; Brogna, Christian ; Formichella, Anna ; Santoro, Antonio ; Salvati, Maurizio. / Radio-induced low-grade glioma : Report of two cases and review of the literature. In: Neurological Sciences. 2009 ; Vol. 30, No. 2. pp. 137-141.
@article{712e36ca2d6d49ac8b76274f98eb98f2,
title = "Radio-induced low-grade glioma: Report of two cases and review of the literature",
abstract = "With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.",
keywords = "Low-grade glioma, Radiation-induced glioma, Radiotherapy",
author = "Alessandro D'Elia and Melone, {Graziella Angelina} and Christian Brogna and Anna Formichella and Antonio Santoro and Maurizio Salvati",
year = "2009",
doi = "10.1007/s10072-009-0017-y",
language = "English",
volume = "30",
pages = "137--141",
journal = "Neurological Sciences",
issn = "1590-1874",
publisher = "Springer-Verlag Italia s.r.l.",
number = "2",

}

TY - JOUR

T1 - Radio-induced low-grade glioma

T2 - Report of two cases and review of the literature

AU - D'Elia, Alessandro

AU - Melone, Graziella Angelina

AU - Brogna, Christian

AU - Formichella, Anna

AU - Santoro, Antonio

AU - Salvati, Maurizio

PY - 2009

Y1 - 2009

N2 - With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.

AB - With the increasing number of cancer survivors, we can observe a population that will present a higher risk of developing secondary long-term toxicities related to adjuvant chemo and radiotherapy regimens. Among these, children surviving from acute lymphoblastic leukemia (ALL) that were treated with prophylactic cranial irradiation represent a group of patients at a high risk of developing secondary brain tumors. Radiation-induced intracranial tumors have been documented since 1950, and today, more than one-hundred cases have been described. We report our experience with two young patients who were hospitalized for low grade gliomas and had a positive anamnesis for ALL and consequent radiotherapy.

KW - Low-grade glioma

KW - Radiation-induced glioma

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=63749106196&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=63749106196&partnerID=8YFLogxK

U2 - 10.1007/s10072-009-0017-y

DO - 10.1007/s10072-009-0017-y

M3 - Article

C2 - 19198758

AN - SCOPUS:63749106196

VL - 30

SP - 137

EP - 141

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

IS - 2

ER -