Radio-induced sarcomas in survivors of Ewing's sarcoma

S. Boriani; P. Picci; A. Sudanese; A. Toni; A. Mancini; G. Frezza; E. Barbieri; N. Baldini; M. Monesi; D. Ciaroni; G. Bacci

Radio-induced sarcomas in survivors of Ewing's sarcoma

S. Boriani, P. Picci, A. Sudanese, A. Toni, A. Mancini, G. Frezza, E. Barbieri, N. Baldini, M. Monesi, D. Ciaroni, G. Bacci

Istituti Ortopedici Rizzoli

Research output: Contribution to journal › Article › peer-review

Abstract

Of 255 cases of Ewing's sarcoma recorded at the Bone Tumor Center of the Rizzoli Orthopaedic Institute, 78 patients (irradiated and with a follow-up of longer than 3 years) were considered 'at risk' for the development of a second radio-induced sarcoma (RIS). Three of the 78 patients developed an RIS in the irradiated field. Theoretical and statistical analyses were carried out considering different modalities of local treatment. Statistically, the only significant factor was related to the irradiation dose. Surgical resection seems to prevent RIS.

Original language	English
Pages (from-to)	545-551
Number of pages	7
Journal	Tumori
Volume	74
Issue number	5
Publication status	Published - 1988

ASJC Scopus subject areas

Cancer Research

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abstract = "Of 255 cases of Ewing's sarcoma recorded at the Bone Tumor Center of the Rizzoli Orthopaedic Institute, 78 patients (irradiated and with a follow-up of longer than 3 years) were considered 'at risk' for the development of a second radio-induced sarcoma (RIS). Three of the 78 patients developed an RIS in the irradiated field. Theoretical and statistical analyses were carried out considering different modalities of local treatment. Statistically, the only significant factor was related to the irradiation dose. Surgical resection seems to prevent RIS.",

author = "S. Boriani and P. Picci and A. Sudanese and A. Toni and A. Mancini and G. Frezza and E. Barbieri and N. Baldini and M. Monesi and D. Ciaroni and G. Bacci",

year = "1988",

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T1 - Radio-induced sarcomas in survivors of Ewing's sarcoma

AU - Boriani, S.

AU - Picci, P.

AU - Sudanese, A.

AU - Toni, A.

AU - Mancini, A.

AU - Frezza, G.

AU - Barbieri, E.

AU - Baldini, N.

AU - Monesi, M.

AU - Ciaroni, D.

AU - Bacci, G.

PY - 1988

Y1 - 1988

N2 - Of 255 cases of Ewing's sarcoma recorded at the Bone Tumor Center of the Rizzoli Orthopaedic Institute, 78 patients (irradiated and with a follow-up of longer than 3 years) were considered 'at risk' for the development of a second radio-induced sarcoma (RIS). Three of the 78 patients developed an RIS in the irradiated field. Theoretical and statistical analyses were carried out considering different modalities of local treatment. Statistically, the only significant factor was related to the irradiation dose. Surgical resection seems to prevent RIS.

AB - Of 255 cases of Ewing's sarcoma recorded at the Bone Tumor Center of the Rizzoli Orthopaedic Institute, 78 patients (irradiated and with a follow-up of longer than 3 years) were considered 'at risk' for the development of a second radio-induced sarcoma (RIS). Three of the 78 patients developed an RIS in the irradiated field. Theoretical and statistical analyses were carried out considering different modalities of local treatment. Statistically, the only significant factor was related to the irradiation dose. Surgical resection seems to prevent RIS.

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AN - SCOPUS:0024301025

VL - 74

SP - 545

EP - 551

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 5

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