Radiofrequency ablation for non-spinal osteoid osteomas in 557 patients

Eugenio Rimondi, Andreas F. Mavrogenis, Giuseppe Rossi, Rosanna Ciminari, Cristina Malaguti, Cristina Tranfaglia, Daniel Vanel, Pietro Ruggieri

Research output: Contribution to journalArticlepeer-review


Objectives To present the results of biopsy and computed tomography (CT) guided radiofrequency ablation (RFA) for non-spinal osteoid osteomas, and compare the results before and after procedural modifications. Methods We retrospectively studied 557 patients with non-spinal osteoid osteomas treated with biopsy and CT-guided RFA. In 68 patients we used 3-mm CT at 2-mm intervals, 19 G/ 5-mm active tip electrodes, and one 4-minute ablation at 90-93C. In 489 patients we used contiguous 1-mm CT, 20 G/5-15-mm electrodes, ablation maintaining 60C for 2 min followed by 14-15 min at 90-93C, and multiple ablations in the same session for large and multiform lesions. Results 533/557 patients (96%) remained asymptomatic and 24/557 (4%) had recurrence; repeat RFA was successful in 22/24 patients (92%). Biopsy was non-diagnostic in 82%. With the modifications performed, success improved from 79% to 98%, recurrences reduced from 21% to 2% and complications from 5.9% to 0.2% (p<0.001). All patients with large and multiform lesions treated with one ablation had recurrence, compared to no patient with similar lesions and multiple ablations in the same session. Conclusion Electrode parameters, duration of ablation, morphology and size of osteoid osteomas are important for RFA. The above modifications are recommended for improved outcome.

Original languageEnglish
Pages (from-to)181-188
Number of pages8
JournalEuropean Radiology
Issue number1
Publication statusPublished - Jan 2012


  • Biopsy
  • CT-guided
  • Osteoid osteoma
  • Radiofrequency ablation
  • Recurrence

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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