Radiofrequency ablation of locally advanced pancreatic adenocarcinoma: An overview

Mirko D'Onofrio, Emilio Barbi, Roberto Girelli, Enrico Martone, Anna Gallotti, Roberto Salvia, Paolo Tinazzi Martini, Claudio Bassi, Paolo Pederzoli, Roberto Pozzi Mucelli

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Radiofrequency ablation (RFA) of pancreatic neoplasms is restricted to locally advanced, non-resectable but nonmetastatic tumors. RFA of pancreatic tumors is nowadays an ultrasound-guided procedure performed during laparotomy in open surgery. Intraoperative ultrasound covers the mandatory role of staging, evaluation of feasibility, guidance and monitoring of the procedure. Different types of needle can be used. The first aim in the evaluation of RFA as a treatment for locally advanced pancreatic ductal adenocarcinoma, in order of evaluation but not of importance, is to determine the feasibility of the procedure. The second aim is to establish the effect of RFA on tumoral mass in terms of necrosis and cytoreduction. The most important aim, third in order of evaluation, is the potential improvement of quality of life and survival rate. Nowadays, only a few studies assess the feasibility of the procedure. The present paper is an overview of RFA for pancreatic adenocarcinoma.

Original languageEnglish
Pages (from-to)3478-3483
Number of pages6
JournalWorld Journal of Gastroenterology
Volume16
Issue number28
DOIs
Publication statusPublished - Jul 28 2010

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Adenocarcinoma
Feasibility Studies
Pancreatic Neoplasms
Laparotomy
Needles
Neoplasms
Necrosis
Survival Rate
Quality of Life

Keywords

  • Contrast-enhanced ultrasound
  • Intraoperative ultrasound
  • Pancreatic adenocarcinoma
  • Perfusion computed tomography
  • Radiofrequency ablation

ASJC Scopus subject areas

  • Gastroenterology

Cite this

D'Onofrio, M., Barbi, E., Girelli, R., Martone, E., Gallotti, A., Salvia, R., ... Mucelli, R. P. (2010). Radiofrequency ablation of locally advanced pancreatic adenocarcinoma: An overview. World Journal of Gastroenterology, 16(28), 3478-3483. https://doi.org/10.3748/wjg.v16.i28.3478

Radiofrequency ablation of locally advanced pancreatic adenocarcinoma : An overview. / D'Onofrio, Mirko; Barbi, Emilio; Girelli, Roberto; Martone, Enrico; Gallotti, Anna; Salvia, Roberto; Martini, Paolo Tinazzi; Bassi, Claudio; Pederzoli, Paolo; Mucelli, Roberto Pozzi.

In: World Journal of Gastroenterology, Vol. 16, No. 28, 28.07.2010, p. 3478-3483.

Research output: Contribution to journalArticle

D'Onofrio, M, Barbi, E, Girelli, R, Martone, E, Gallotti, A, Salvia, R, Martini, PT, Bassi, C, Pederzoli, P & Mucelli, RP 2010, 'Radiofrequency ablation of locally advanced pancreatic adenocarcinoma: An overview', World Journal of Gastroenterology, vol. 16, no. 28, pp. 3478-3483. https://doi.org/10.3748/wjg.v16.i28.3478
D'Onofrio, Mirko ; Barbi, Emilio ; Girelli, Roberto ; Martone, Enrico ; Gallotti, Anna ; Salvia, Roberto ; Martini, Paolo Tinazzi ; Bassi, Claudio ; Pederzoli, Paolo ; Mucelli, Roberto Pozzi. / Radiofrequency ablation of locally advanced pancreatic adenocarcinoma : An overview. In: World Journal of Gastroenterology. 2010 ; Vol. 16, No. 28. pp. 3478-3483.
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