Abstract
The usefulness of radioimmunoguided endoscopy in the detection of primary and recurrent rectal cancer was investigated. Of the 15 patients included in our study, 4 with suspected primary rectal cancer were examined preoperatively, while the remaining 11 were studied after radical resection of rectal carcinoma with the aim of detecting local recurrence. Radioimmunoguided endoscopy was performed employing a hand-held gamma-detecting probe (mod. 2 Oris, France), after the administration of a 111In labeled monoclonal antibody to CEA. Radioimmuno-guided endoscopy results detected the presence of primary or recurrent periluminal cancer in seven cases. In four it modified the preoperative stage based on the findings of conventional investigation and it influenced the surgical decision in five cases. No toxicity was noted and none of the patients developed HAMAs.
| Original language | English |
|---|---|
| Pages (from-to) | 155-158 |
| Number of pages | 4 |
| Journal | International Journal of Colorectal Disease |
| Volume | 7 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 1992 |
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ASJC Scopus subject areas
- Gastroenterology
Cite this
Radioimmuno-guided endoscopy (RIGE) in the detection of primary and recurrent rectal tumor. / Prati, U.; Roveda, L.; Butera, R.; Nazari, S.; Trespi, E.; Aprile, C.; Zonta, A.
In: International Journal of Colorectal Disease, Vol. 7, No. 3, 09.1992, p. 155-158.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radioimmuno-guided endoscopy (RIGE) in the detection of primary and recurrent rectal tumor
AU - Prati, U.
AU - Roveda, L.
AU - Butera, R.
AU - Nazari, S.
AU - Trespi, E.
AU - Aprile, C.
AU - Zonta, A.
PY - 1992/9
Y1 - 1992/9
N2 - The usefulness of radioimmunoguided endoscopy in the detection of primary and recurrent rectal cancer was investigated. Of the 15 patients included in our study, 4 with suspected primary rectal cancer were examined preoperatively, while the remaining 11 were studied after radical resection of rectal carcinoma with the aim of detecting local recurrence. Radioimmunoguided endoscopy was performed employing a hand-held gamma-detecting probe (mod. 2 Oris, France), after the administration of a 111In labeled monoclonal antibody to CEA. Radioimmuno-guided endoscopy results detected the presence of primary or recurrent periluminal cancer in seven cases. In four it modified the preoperative stage based on the findings of conventional investigation and it influenced the surgical decision in five cases. No toxicity was noted and none of the patients developed HAMAs.
AB - The usefulness of radioimmunoguided endoscopy in the detection of primary and recurrent rectal cancer was investigated. Of the 15 patients included in our study, 4 with suspected primary rectal cancer were examined preoperatively, while the remaining 11 were studied after radical resection of rectal carcinoma with the aim of detecting local recurrence. Radioimmunoguided endoscopy was performed employing a hand-held gamma-detecting probe (mod. 2 Oris, France), after the administration of a 111In labeled monoclonal antibody to CEA. Radioimmuno-guided endoscopy results detected the presence of primary or recurrent periluminal cancer in seven cases. In four it modified the preoperative stage based on the findings of conventional investigation and it influenced the surgical decision in five cases. No toxicity was noted and none of the patients developed HAMAs.
UR - http://www.scopus.com/inward/record.url?scp=0026658271&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026658271&partnerID=8YFLogxK
U2 - 10.1007/BF00360357
DO - 10.1007/BF00360357
M3 - Article
VL - 7
SP - 155
EP - 158
JO - International Journal of Colorectal Disease
JF - International Journal of Colorectal Disease
SN - 0179-1958
IS - 3
ER -