Radioimmuno-guided endoscopy (RIGE) in the detection of primary and recurrent rectal tumor

U. Prati, L. Roveda, R. Butera, S. Nazari, E. Trespi, C. Aprile, A. Zonta

Research output: Contribution to journalArticlepeer-review

Abstract

The usefulness of radioimmunoguided endoscopy in the detection of primary and recurrent rectal cancer was investigated. Of the 15 patients included in our study, 4 with suspected primary rectal cancer were examined preoperatively, while the remaining 11 were studied after radical resection of rectal carcinoma with the aim of detecting local recurrence. Radioimmunoguided endoscopy was performed employing a hand-held gamma-detecting probe (mod. 2 Oris, France), after the administration of a 111In labeled monoclonal antibody to CEA. Radioimmuno-guided endoscopy results detected the presence of primary or recurrent periluminal cancer in seven cases. In four it modified the preoperative stage based on the findings of conventional investigation and it influenced the surgical decision in five cases. No toxicity was noted and none of the patients developed HAMAs.

Original languageEnglish
Pages (from-to)155-158
Number of pages4
JournalInternational Journal of Colorectal Disease
Volume7
Issue number3
DOIs
Publication statusPublished - Sep 1992

ASJC Scopus subject areas

  • Gastroenterology

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