A radioimmunoassay for determination of digoxin in human plasma is described. After extraction of plasma with ethyl acetate, the radioimmunoassay is performed using an antiserum to digoxin BSA and charcoal. Precision, accuracy, sensitivity and specificity were evaluated. The comparison of two methods based on the direct measurement of digoxin without extraction showed the presence of aspecific interferences coming from human plasma when plasma samples are not extracted.
|Title of host publication||Journal of Nuclear Biology and Medicine|
|Number of pages||7|
|Publication status||Published - 1975|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging