Abstract
Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing 111In anti-CEA, F(ab′)2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the 111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS.
| Original language | English |
|---|---|
| Pages (from-to) | 51-52 |
| Number of pages | 2 |
| Journal | International Journal of Radiation Applications and Instrumentation. |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1991 |
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Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′)2 . / Aprile, C.; Prati, U.; Saponaro, R.; Roveda, L.; Carena, M.; Gastaldo, L.
In: International Journal of Radiation Applications and Instrumentation., Vol. 18, No. 1, 1991, p. 51-52.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′)2
AU - Aprile, C.
AU - Prati, U.
AU - Saponaro, R.
AU - Roveda, L.
AU - Carena, M.
AU - Gastaldo, L.
PY - 1991
Y1 - 1991
N2 - Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing 111In anti-CEA, F(ab′)2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the 111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS.
AB - Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing 111In anti-CEA, F(ab′)2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the 111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS.
UR - http://www.scopus.com/inward/record.url?scp=44949281913&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44949281913&partnerID=8YFLogxK
U2 - 10.1016/0883-2897(91)90046-N
DO - 10.1016/0883-2897(91)90046-N
M3 - Article
VL - 18
SP - 51
EP - 52
JO - Nuclear Medicine and Biology
JF - Nuclear Medicine and Biology
SN - 0969-8051
IS - 1
ER -