Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′)2

C. Aprile, U. Prati, R. Saponaro, L. Roveda, M. Carena, L. Gastaldo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Thirty-two immunoscintigraphic studies have been performed in 26 patients previously operated upon for rectosigmoid cancer, for an early detection of pelvic recurrence, employing 111In anti-CEA, F(ab′)2. The sensitivity was 1, specificity 0.76 and accuracy 0.84, leading to a positive predictive value of 0.69 and a negative value of 1. The combined use of a non-imaging surgical probe in 6 of the 10 patients who underwent second look surgery, detecting the 111In radioactivity used for RIS, improved diagnostic accuracy, ruling out the presence of tumors in 3 patients with false positive RIS.

Original languageEnglish
Pages (from-to)51-52
Number of pages2
JournalInternational Journal of Radiation Applications and Instrumentation.
Volume18
Issue number1
DOIs
Publication statusPublished - 1991

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Recurrence
Second-Look Surgery
Neoplasms
Early Detection of Cancer
Radioactivity

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Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′)2 . / Aprile, C.; Prati, U.; Saponaro, R.; Roveda, L.; Carena, M.; Gastaldo, L.

In: International Journal of Radiation Applications and Instrumentation., Vol. 18, No. 1, 1991, p. 51-52.

Research output: Contribution to journalArticle

Aprile, C. ; Prati, U. ; Saponaro, R. ; Roveda, L. ; Carena, M. ; Gastaldo, L. / Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab′)2 . In: International Journal of Radiation Applications and Instrumentation. 1991 ; Vol. 18, No. 1. pp. 51-52.
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