Radiology of pancreatic adenocarcinoma: Current status of imaging

Dushyant V. Sahani, Zarine K. Shah, Onofrio A. Catalano, Giles W. Boland, William R. Brugge

Research output: Contribution to journalArticle

Abstract

Pancreatic adenocarcinoma is one of the leading causes of cancer death in the West, with a poor overall 5-year survival rate of only 4%. Late clinical presentation with an advanced disease results in a low rate of surgical intervention. Tumor serum marker CA 19-9 is sensitive, although not specific for the diagnosis of adenocarcinomas of the pancreas. The treatment approach is based on whether the tumor is resectable or non-resectable at presentation. Therefore, imaging plays a crucial role in the management of this disease. Many modalities are available to image the pancreas. They include non-invasive techniques, like ultrasound, contrast-enhanced multidetector computed tomography, magnetic resonance imaging and integrated positron emission tomography/computed tomography, and invasive techniques, like endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. Each of these modalities has its peculiar strengths and weaknesses.

Original languageEnglish
Pages (from-to)23-33
Number of pages11
JournalJournal of Gastroenterology and Hepatology
Volume23
Issue number1
DOIs
Publication statusPublished - 2008

Keywords

  • Adenocarcinoma
  • Endoscopic ultrasound
  • Multidetector computed tomography
  • Pancreas
  • Positron emission tomography/computed tomography

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

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