Radionuclide assessment of left ventricular function in patients with myocardial infarction and diabetes mellitus

A. Lomuscio, A. Bestetti, D. Vergani, D. Chiaramello, A. Chiti, L. Ruffini, L. Pozzoni, G. L. Tarolo

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to compare left ventricular function, assessed by radionuclide angiocardiography, in 54 diabetics and 194 non-diabetics with acute myocardial infarction (AMI). The most meaningful results concern the inferior AMI group, whose left ventricular ejection fraction (LVEF) and regional wall motion were significantly lower in diabetics than in non-diabetics (LVEF was 44.2 ± 11 vs. 51.6 ± 9%, P <0.005; the regional wall motion score was 0.46 ± 1 vs. 1.56 ± 1, P <0.01, respectively), while no significant difference was observed in the anterior AMI group. However, in the group as a whole, the LVEF was 41 ± 13% in diabetics and 47 ± 13% in non-diabetics (P <0.01), the number of abnormally contracting segments was 2.0 ± 0.9 and 1.5 ± 1, respectively, and the wall motion score was 0.2 ± 1.1 and 1.0 ± 1.4, respectively (P <0.01). These data could be explained by an underlying cardiac dysfunction in diabetes, in addition to AMI. The more marked difference between diabetics and non-diabetics in inferior AMI might be related to the smaller infarct size in this group.

Original languageEnglish
Pages (from-to)73-76
Number of pages4
JournalJournal of Internal Medicine
Volume231
Issue number1
Publication statusPublished - 1992

Keywords

  • Acute myocardial infarction
  • Diabetes mellitus
  • Equilibrium gated radionuclide angiocardiography
  • Left ventricular function

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'Radionuclide assessment of left ventricular function in patients with myocardial infarction and diabetes mellitus'. Together they form a unique fingerprint.

Cite this