Radionuclide monitoring of cardiac adaptations to volume loading in patients with dilated cardiomyopathy and mild heart failure: Effects of angiotensin-converting enzyme inhibition

M. Volpe; M. A E Rao; A. Cuocolo; R. Russo; A. Nappi; A. F. Mele; I. Enea; B. Trimarco; M. Condorelli

Radionuclide monitoring of cardiac adaptations to volume loading in patients with dilated cardiomyopathy and mild heart failure: Effects of angiotensin-converting enzyme inhibition

M. Volpe, M. A E Rao, A. Cuocolo, R. Russo, A. Nappi, A. F. Mele, I. Enea, B. Trimarco, M. Condorelli

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Cardiac adaptations to volume overload have been poorly investigated in heart failure. The aim of this study was to assess dynamic left ventricular responses to acute volume loading by continuous radionuclide monitoring in patients with asymptomatic to mildly symptomatic left ventricular dysfunction. Methods and Results: Left ventricular end-diastolic (EDV) and end-systolic (ESV) volumes, ejection fraction (EF), and peak filling rate (PFR) were monitored by a radionuclide detector (Vest) before and during volume expansion (sodium chloride, 0.9%, 0.25 mL · kg^-1 · min^-1 for 2 hours) in 10 patients with idiopathic dilated cardiomyopathy (DCM) and mild heart failure (New York Heart Association class I or II, ejection fraction

Original language	English
Pages (from-to)	2511-2518
Number of pages	8
Journal	Circulation
Volume	92
Issue number	9
Publication status	Published - 1995

Keywords

cardiomyopathy
radioisotopes
ventricles

ASJC Scopus subject areas

Physiology
Cardiology and Cardiovascular Medicine

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Radionuclide monitoring of cardiac adaptations to volume loading in patients with dilated cardiomyopathy and mild heart failure : Effects of angiotensin-converting enzyme inhibition. / Volpe, M.; Rao, M. A E; Cuocolo, A.; Russo, R.; Nappi, A.; Mele, A. F.; Enea, I.; Trimarco, B.; Condorelli, M.

In: Circulation, Vol. 92, No. 9, 1995, p. 2511-2518.

Research output: Contribution to journal › Article › peer-review

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abstract = "Background: Cardiac adaptations to volume overload have been poorly investigated in heart failure. The aim of this study was to assess dynamic left ventricular responses to acute volume loading by continuous radionuclide monitoring in patients with asymptomatic to mildly symptomatic left ventricular dysfunction. Methods and Results: Left ventricular end-diastolic (EDV) and end-systolic (ESV) volumes, ejection fraction (EF), and peak filling rate (PFR) were monitored by a radionuclide detector (Vest) before and during volume expansion (sodium chloride, 0.9%, 0.25 mL · kg-1 · min-1 for 2 hours) in 10 patients with idiopathic dilated cardiomyopathy (DCM) and mild heart failure (New York Heart Association class I or II, ejection fraction ",

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AU - Cuocolo, A.

AU - Russo, R.

AU - Nappi, A.

AU - Mele, A. F.

AU - Enea, I.

AU - Trimarco, B.

AU - Condorelli, M.

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