Abstract
Background: Cardiac adaptations to volume overload have been poorly investigated in heart failure. The aim of this study was to assess dynamic left ventricular responses to acute volume loading by continuous radionuclide monitoring in patients with asymptomatic to mildly symptomatic left ventricular dysfunction. Methods and Results: Left ventricular end-diastolic (EDV) and end-systolic (ESV) volumes, ejection fraction (EF), and peak filling rate (PFR) were monitored by a radionuclide detector (Vest) before and during volume expansion (sodium chloride, 0.9%, 0.25 mL · kg-1 · min-1 for 2 hours) in 10 patients with idiopathic dilated cardiomyopathy (DCM) and mild heart failure (New York Heart Association class I or II, ejection fraction
Original language | English |
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Pages (from-to) | 2511-2518 |
Number of pages | 8 |
Journal | Circulation |
Volume | 92 |
Issue number | 9 |
Publication status | Published - 1995 |
Keywords
- cardiomyopathy
- radioisotopes
- ventricles
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine