Abstract
After brief notes on techniques used to radiate the spine, its indications and the limits of doses required by its adjacency to the spinal cord, our experience in the treatment of 28 patients with a diagnosis of Ewing's sarcoma localized in the spine, not metastatic at onset, that came to our observation between 1980 and 1994 is reported. All of the patients were treated by chemotherapy. As for local treatment radiotherapy was performed in all of the cases, in 50% of cases it was associated with surgery (6 laminectomies, 6 excisions, and 2 vertebrectomies). Five-year survival rate was 43.5%. The prognosis of this group of patients was intermediate among forms localized in the limbs and those localized in the pelvis. There is a greater frequency of cerebral (20%) and skeletal metastases (55%) as compared to the disease that occurred in other sites where secondary pulmonary localizations generally prevailed. Local control was similar for disease occurring in other sites despite the need to deliver doses that were lower than those typically used for this pathology in regions above the cauda.
| Original language | English |
|---|---|
| Pages (from-to) | 105-111 |
| Number of pages | 7 |
| Journal | La Chirurgia degli organi di movimento |
| Volume | 83 |
| Issue number | 1-2 |
| Publication status | Published - 1998 |
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Radiotherapy in vertebral tumors. Indications and limits : a report on 28 cases of Ewing's sarcoma of the spine. / Barbieri, E.; Chiaulon, G.; Bunkeila, F.; Putti, C.; Frezza, G.; Neri, S.; Boriani, S.; Campanacci, M.; Babini, L.
In: La Chirurgia degli organi di movimento, Vol. 83, No. 1-2, 1998, p. 105-111.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radiotherapy in vertebral tumors. Indications and limits
T2 - a report on 28 cases of Ewing's sarcoma of the spine.
AU - Barbieri, E.
AU - Chiaulon, G.
AU - Bunkeila, F.
AU - Putti, C.
AU - Frezza, G.
AU - Neri, S.
AU - Boriani, S.
AU - Campanacci, M.
AU - Babini, L.
PY - 1998
Y1 - 1998
N2 - After brief notes on techniques used to radiate the spine, its indications and the limits of doses required by its adjacency to the spinal cord, our experience in the treatment of 28 patients with a diagnosis of Ewing's sarcoma localized in the spine, not metastatic at onset, that came to our observation between 1980 and 1994 is reported. All of the patients were treated by chemotherapy. As for local treatment radiotherapy was performed in all of the cases, in 50% of cases it was associated with surgery (6 laminectomies, 6 excisions, and 2 vertebrectomies). Five-year survival rate was 43.5%. The prognosis of this group of patients was intermediate among forms localized in the limbs and those localized in the pelvis. There is a greater frequency of cerebral (20%) and skeletal metastases (55%) as compared to the disease that occurred in other sites where secondary pulmonary localizations generally prevailed. Local control was similar for disease occurring in other sites despite the need to deliver doses that were lower than those typically used for this pathology in regions above the cauda.
AB - After brief notes on techniques used to radiate the spine, its indications and the limits of doses required by its adjacency to the spinal cord, our experience in the treatment of 28 patients with a diagnosis of Ewing's sarcoma localized in the spine, not metastatic at onset, that came to our observation between 1980 and 1994 is reported. All of the patients were treated by chemotherapy. As for local treatment radiotherapy was performed in all of the cases, in 50% of cases it was associated with surgery (6 laminectomies, 6 excisions, and 2 vertebrectomies). Five-year survival rate was 43.5%. The prognosis of this group of patients was intermediate among forms localized in the limbs and those localized in the pelvis. There is a greater frequency of cerebral (20%) and skeletal metastases (55%) as compared to the disease that occurred in other sites where secondary pulmonary localizations generally prevailed. Local control was similar for disease occurring in other sites despite the need to deliver doses that were lower than those typically used for this pathology in regions above the cauda.
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UR - http://www.scopus.com/inward/citedby.url?scp=0031615560&partnerID=8YFLogxK
M3 - Article
C2 - 9718819
AN - SCOPUS:0031615560
VL - 83
SP - 105
EP - 111
JO - Chirurgia degli Organi di Movimento
JF - Chirurgia degli Organi di Movimento
SN - 0009-4749
IS - 1-2
ER -