RADIOTERAPIA DEL CARCINOMA CERVICALE IN STADIO AVANZATO

Translated title of the contribution: Radiotherapy of advanced cervical carcinomas

F. Volterrani, S. Tana, N. Trenti

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty nine stage II-distal (i.e. with involvement of medium third of parametrium and/or vagina), 220 stage III and 5 stage IV cervical carcinomas were treated with radiotherapy alone (combination of intracavitary radiumtherapy and megavoltage external irradiation on the pelvis) in the years 1971-79. The 5-year relapse free survival by actuarial method was 52.0% for stage II-distal and 40.6% for stage III, while all stage IV patients relapsed within the third year from the start of the treatment. Failures were pelvic recurrence in 98/227 patients with follow-up ≥1 year (43.2%), distant metastases in 15 (6.7%), pelvic plus distant relapse in 10 (4.4%) and 2nd tumor in 2 (0.9%). In stage III patients the renal exclusion and positivity at lymphography were the major adverse prognostic factors and 5-year relapse free survival was respectively 28.5% and 19.6%. Improvement of the results can probably derive from a combined therapeutic approach with chemotherapy and radiotherapy in a sequential scheme.

Translated title of the contributionRadiotherapy of advanced cervical carcinomas
Original languageItalian
Pages (from-to)388-392
Number of pages5
JournalRadiologia Medica
Volume70
Issue number6
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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