Abstract
Background: The lesions of the various forms of Kaposi's sarcoma (KS), which are relatively radiosensitive, have been treated with different modalities of radiotherapy, with heterogeneous aims and results. Objective: To verify the effectiveness and safety of radiotherapy on a large number of lesions endowed (classic KS) with a prolonged follow-up. Methods: A retrospective study was done on 711 lesions of classic KS and 771 lesions of human immunodeficiency virus (HIV)-related KS, treated with traditional X-ray therapy. Results: In classic KS, a cure rate of 98.7% resulted after 13.5 years from the end of radiotherapy. In three lesions (0.42%) in the same patient, an acute radiodermatitis occurred after traumatic action. In HIV-related KS, a complete remission was obtained in 91.43% of the lesions, partial remission in 6.74% and non-response in 0.51% at 1 to 46 months from the end of radiotherapy. Conclusion: Radiotherapy showed tobe a safe and effective method, with relevant importance in the therapeutic strategy of KS.
| Original language | English |
|---|---|
| Pages (from-to) | 297-302 |
| Number of pages | 6 |
| Journal | Journal of the European Academy of Dermatology and Venereology |
| Volume | 22 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2008 |
Fingerprint
Keywords
- Classic Kaposi's sarcoma
- HIV-related Kaposi's sarcoma
- Radio therapy
ASJC Scopus subject areas
- Dermatology
- Infectious Diseases
Cite this
Radiotherapy of classic and human immunodeficiency virus-related Kaposi's sarcoma : Results in 1482 lesions. / Caccialanza, M.; Marca, S.; Piccinno, R.; Eulisse, G.
In: Journal of the European Academy of Dermatology and Venereology, Vol. 22, No. 3, 03.2008, p. 297-302.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radiotherapy of classic and human immunodeficiency virus-related Kaposi's sarcoma
T2 - Results in 1482 lesions
AU - Caccialanza, M.
AU - Marca, S.
AU - Piccinno, R.
AU - Eulisse, G.
PY - 2008/3
Y1 - 2008/3
N2 - Background: The lesions of the various forms of Kaposi's sarcoma (KS), which are relatively radiosensitive, have been treated with different modalities of radiotherapy, with heterogeneous aims and results. Objective: To verify the effectiveness and safety of radiotherapy on a large number of lesions endowed (classic KS) with a prolonged follow-up. Methods: A retrospective study was done on 711 lesions of classic KS and 771 lesions of human immunodeficiency virus (HIV)-related KS, treated with traditional X-ray therapy. Results: In classic KS, a cure rate of 98.7% resulted after 13.5 years from the end of radiotherapy. In three lesions (0.42%) in the same patient, an acute radiodermatitis occurred after traumatic action. In HIV-related KS, a complete remission was obtained in 91.43% of the lesions, partial remission in 6.74% and non-response in 0.51% at 1 to 46 months from the end of radiotherapy. Conclusion: Radiotherapy showed tobe a safe and effective method, with relevant importance in the therapeutic strategy of KS.
AB - Background: The lesions of the various forms of Kaposi's sarcoma (KS), which are relatively radiosensitive, have been treated with different modalities of radiotherapy, with heterogeneous aims and results. Objective: To verify the effectiveness and safety of radiotherapy on a large number of lesions endowed (classic KS) with a prolonged follow-up. Methods: A retrospective study was done on 711 lesions of classic KS and 771 lesions of human immunodeficiency virus (HIV)-related KS, treated with traditional X-ray therapy. Results: In classic KS, a cure rate of 98.7% resulted after 13.5 years from the end of radiotherapy. In three lesions (0.42%) in the same patient, an acute radiodermatitis occurred after traumatic action. In HIV-related KS, a complete remission was obtained in 91.43% of the lesions, partial remission in 6.74% and non-response in 0.51% at 1 to 46 months from the end of radiotherapy. Conclusion: Radiotherapy showed tobe a safe and effective method, with relevant importance in the therapeutic strategy of KS.
KW - Classic Kaposi's sarcoma
KW - HIV-related Kaposi's sarcoma
KW - Radio therapy
UR - http://www.scopus.com/inward/record.url?scp=39049099844&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=39049099844&partnerID=8YFLogxK
U2 - 10.1111/j.1468-3083.2007.02405.x
DO - 10.1111/j.1468-3083.2007.02405.x
M3 - Article
C2 - 18269597
AN - SCOPUS:39049099844
VL - 22
SP - 297
EP - 302
JO - Journal of the European Academy of Dermatology and Venereology
JF - Journal of the European Academy of Dermatology and Venereology
SN - 0926-9959
IS - 3
ER -