Background. Incompletely excised basal and squamous cell carcinomas of the skin (with histopathological ascertainment) with no evidence of clinical disease represent a yet unsolved therapeutic problem. Aim of this study was to evaluate whether radiotherapy was or not a safe and effective treatment in destroying the residual neoplastic cells and to prevent and/or reduce the onset of clinically evident relapses. Methods. Therefore, a retrospective study was performed on 87 patients (77 with basal cell carcinoma and 10 with squamous cell carcinoma), that underwent orthovoltage radiotherapy in the period 1982-1999. The total doses administered ranged from 50 to 60 Gy. The mean follow-up was 46.37 months, planned according to a schedule of a first control 1 month after the end of radiotherapy, then a control every sixth month for 5 years, and a control once in a year. The cure-rate was evaluated according to the life-table method. Results. The five-year cure-rate (after the end of radiotherapy) was 90.4%. Five recurrences have been observed in basal cell carcinomas, 2 centrally and 3 marginally respect to the irradiation field. The cosmetic results were evaluated as good or acceptable in 81% of cases. So far no complications nor sequelae to the treatment have been observed. Conclusions. Radiotherapy has resulted as a safe and effective treatment with a low cost in the management of this kind of skin neoplasms.
|Number of pages||5|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 2001|
- Carcinoma, basal cell
- Carcinoma, squamous cell
- Skin neoplasms, surgery
ASJC Scopus subject areas