Raising awareness of non-hodgkin lymphoma in HIV-infected adolescents: Report of 2 cases in the HAART era

Paola Zangari, Veronica Santilli, Nicola Cotugno, Emma Manno, Giuseppe Palumbo, Alessandra Lombardi, Rita De Vito, Hyppolite Tchidjou, Stefania Baldassari, Paola Ariganello, Giuseppe Pontrelli, Francesca De Florio, Paolo Palma, Stefania Bernardi

Research output: Contribution to journalArticle

Abstract

Human immunodeficiency virus (HIV) chronically infected patients are at increased risk of developing non-Hodgkin lymphoma compared with the general population. Highly active antiretroviral therapy has had a dramatic effect on the natural history of HIV infection, reducing the incidence of acquired immunodeficiency syndrome-related non-Hodgkin lymphoma and improving overall survival. However, problems related to adherence to treatment, frequently experienced during adolescence, may increase the risk of acquired immunodeficiency syndrome-related cancers. Optimizing highly active antiretroviral therapy and monitoring noncompliant patients with persisting HIV replication should be considered by physicians who take care of these patients. We herein report 2 cases of relapsed/progressive Burkitt lymphoma in HIV vertically infected adolescents.

Original languageEnglish
JournalJournal of Pediatric Hematology/Oncology
Volume35
Issue number3
DOIs
Publication statusPublished - Apr 2013

Keywords

  • Burkitt lymphoma
  • HAART adherence
  • HIV-infected adolescents
  • Non-Hodgkin lymphoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

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