Random biopsy: When, how many and where to take the cores?

Vincenzo Scattoni, Carmen Maccagnano, Umberto Capitanio, Andrea Gallina, Alberto Briganti, Francesco Montorsi

Research output: Contribution to journalArticlepeer-review


Purpose: The optimal random prostate biopsy scheme (PBx) in the initial and repeated setting is still an issue of controversy. We performed an analysis of the recent literature about the prostate biopsy techniques. Methods: We performed a clinical and critical literature review by searching MEDLINE database from January 2005 up to January 2014. Electronic searches were limited to the English language, and the keywords prostate cancer, prostate biopsy, transrectal ultrasound, transperineal prostate biopsy were used. Results: Prostate biopsy strategy in initial setting. According to the literature and the major international guidelines, the recommended approach in initial setting is still the extended scheme (EPBx) (12 cores). However, there is now a growing evidence in the literature that (a) saturation PBx (>20 cores) (SPBx) might be indicated in patients with PSA

Original languageEnglish
Pages (from-to)859-869
Number of pages11
JournalWorld Journal of Urology
Issue number4
Publication statusPublished - 2014


  • Prostate biopsy
  • Prostate cancer
  • Transperineal prostate biopsy
  • Transrectal ultrasound

ASJC Scopus subject areas

  • Urology
  • Medicine(all)


Dive into the research topics of 'Random biopsy: When, how many and where to take the cores?'. Together they form a unique fingerprint.

Cite this