Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis

A. Maggioni; P. Benedetti Panici; T. Dell'Anna; F. Landoni; A. Lissoni; A. Pellegrino; R. S. Rossi; S. Chiari; E. Campagnutta; S. Greggi; R. Angioli; N. Manci; M. Calcagno; G. Scambia; R. Fossati; I. Floriani; V. Torri; R. Grassi; C. Mangioni

doi:10.1038/sj.bjc.6603323

Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis

A. Maggioni, P. Benedetti Panici, T. Dell'Anna, F. Landoni, A. Lissoni, A. Pellegrino, R. S. Rossi, S. Chiari, E. Campagnutta, S. Greggi, R. Angioli, N. Manci, M. Calcagno, G. Scambia, R. Fossati, I. Floriani, V. Torri, R. Grassi, C. Mangioni

Research output: Contribution to journal › Article › peer-review

Abstract

No randomised trials have addressed the value of systematic aortic and pelvic lymphadenectomy (SL) in ovarian cancer macroscopically confined to the pelvis. This study was conducted to investigate the role of SL compared with lymph nodes sampling (CONTROL) in the management of early stage ovarian cancer. A total of 268 eligible patients with macroscopically intrapelvic ovarian carcinoma were randomised to SL (N = 138) or CONTROL (N = 130). The primary objective was to compare the proportion of patients with retroperitoneal nodal involvement between the two groups. Median operating time was longer and more patients required blood transfusions in the SL arm than the CONTROL arm (240 vs 150 min, P

Original language	English
Pages (from-to)	699-704
Number of pages	6
Journal	British Journal of Cancer
Volume	95
Issue number	6
DOIs	https://doi.org/10.1038/sj.bjc.6603323
Publication status	Published - Sep 18 2006

Keywords

Lymphadenectomy
Ovarian carcinoma
Randomised clinical trial
Surgery

ASJC Scopus subject areas

Cancer Research
Oncology

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10.1038/sj.bjc.6603323

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Maggioni, A., Panici, P. B., Dell'Anna, T., Landoni, F., Lissoni, A., Pellegrino, A., Rossi, R. S., Chiari, S., Campagnutta, E., Greggi, S., Angioli, R., Manci, N., Calcagno, M., Scambia, G., Fossati, R., Floriani, I., Torri, V., Grassi, R., & Mangioni, C. (2006). Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis. British Journal of Cancer, 95(6), 699-704. https://doi.org/10.1038/sj.bjc.6603323

Maggioni, A, Panici, PB, Dell'Anna, T, Landoni, F, Lissoni, A, Pellegrino, A, Rossi, RS, Chiari, S, Campagnutta, E, Greggi, S, Angioli, R, Manci, N, Calcagno, M, Scambia, G, Fossati, R, Floriani, I, Torri, V, Grassi, R & Mangioni, C 2006, 'Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis', British Journal of Cancer, vol. 95, no. 6, pp. 699-704. https://doi.org/10.1038/sj.bjc.6603323

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abstract = "No randomised trials have addressed the value of systematic aortic and pelvic lymphadenectomy (SL) in ovarian cancer macroscopically confined to the pelvis. This study was conducted to investigate the role of SL compared with lymph nodes sampling (CONTROL) in the management of early stage ovarian cancer. A total of 268 eligible patients with macroscopically intrapelvic ovarian carcinoma were randomised to SL (N = 138) or CONTROL (N = 130). The primary objective was to compare the proportion of patients with retroperitoneal nodal involvement between the two groups. Median operating time was longer and more patients required blood transfusions in the SL arm than the CONTROL arm (240 vs 150 min, P ",

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AU - Lissoni, A.

AU - Pellegrino, A.

AU - Rossi, R. S.

AU - Chiari, S.

AU - Campagnutta, E.

AU - Greggi, S.

AU - Angioli, R.

AU - Manci, N.

AU - Calcagno, M.

AU - Scambia, G.

AU - Fossati, R.

AU - Floriani, I.

AU - Torri, V.

AU - Grassi, R.

AU - Mangioni, C.

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KW - Ovarian carcinoma

KW - Randomised clinical trial

KW - Surgery

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Randomised study of systematic lymphadenectomy in patients with epithelial ovarian cancer macroscopically confined to the pelvis

Abstract

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