Synopsis Objective To investigate the effects of topical application of a Gold Silk Sericin (GSS) complex on biophysical parameters related to skin ageing. Methods A range of non-invasive bioengineering methods were deployed in an 8-week randomized, double-blinded, vehicle-controlled, split-face study among 40 female subjects aged 40-70. Endpoints measured included expert grades of skin condition, stratum corneum (SC) hydration, SC barrier function, elasticity and surface topography. Results The GSS complex produced significant single-variable (P <0.05) improvements in SC hydration, barrier function, elasticity and surface topography compared with the Vehicle control. Conclusion The GSS complex examined in this study represents an interesting new cosmetic topical technology with which to address multiple aspects of aged/photoaged female facial skin.
- hair + body care
- skin repair/acne/rosacea/dandruff/striae
ASJC Scopus subject areas
- Colloid and Surface Chemistry
- Drug Discovery
- Pharmaceutical Science
- Chemistry (miscellaneous)