Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report

Eugenio Pozzati, Mino Zucchelli, Mario Schiavina, Paola Contini, Maria Pia Foschini

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.

Original languageEnglish
Pages (from-to)671-674
Number of pages4
JournalSurgical Neurology
Volume68
Issue number6
DOIs
Publication statusPublished - Dec 2007

Fingerprint

Lymphangioleiomyomatosis
Meningioma
Progesterone
Growth
Interstitial Lung Diseases
Estrogens
Therapeutics
lipoarabinomannan

Keywords

  • Lymphangioleiomyomatosis
  • Meningioma
  • Progesterone
  • Tuberous sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis : case report. / Pozzati, Eugenio; Zucchelli, Mino; Schiavina, Mario; Contini, Paola; Foschini, Maria Pia.

In: Surgical Neurology, Vol. 68, No. 6, 12.2007, p. 671-674.

Research output: Contribution to journalArticle

Pozzati, Eugenio ; Zucchelli, Mino ; Schiavina, Mario ; Contini, Paola ; Foschini, Maria Pia. / Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis : case report. In: Surgical Neurology. 2007 ; Vol. 68, No. 6. pp. 671-674.
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