Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report

Eugenio Pozzati, Mino Zucchelli, Mario Schiavina, Paola Contini, Maria Pia Foschini

Research output: Contribution to journalArticle

Abstract

Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.

Original languageEnglish
Pages (from-to)671-674
Number of pages4
JournalSurgical Neurology
Volume68
Issue number6
DOIs
Publication statusPublished - Dec 2007

Keywords

  • Lymphangioleiomyomatosis
  • Meningioma
  • Progesterone
  • Tuberous sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Fingerprint Dive into the research topics of 'Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report'. Together they form a unique fingerprint.

  • Cite this