Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report

Eugenio Pozzati; Mino Zucchelli; Mario Schiavina; Paola Contini; Maria Pia Foschini

doi:10.1016/j.surneu.2006.11.063

Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report

Eugenio Pozzati, Mino Zucchelli, Mario Schiavina, Paola Contini, Maria Pia Foschini

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article

Abstract

Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.

Original language	English
Pages (from-to)	671-674
Number of pages	4
Journal	Surgical Neurology
Volume	68
Issue number	6
DOIs	https://doi.org/10.1016/j.surneu.2006.11.063
Publication status	Published - Dec 2007

Keywords

Lymphangioleiomyomatosis
Meningioma
Progesterone
Tuberous sclerosis

ASJC Scopus subject areas

Clinical Neurology
Surgery

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Pozzati, E., Zucchelli, M., Schiavina, M., Contini, P., & Foschini, M. P. (2007). Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis: case report. Surgical Neurology, 68(6), 671-674. https://doi.org/10.1016/j.surneu.2006.11.063

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