Abstract
Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 671-674 |
| Number of pages | 4 |
| Journal | Surgical Neurology |
| Volume | 68 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2007 |
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Keywords
- Lymphangioleiomyomatosis
- Meningioma
- Progesterone
- Tuberous sclerosis
ASJC Scopus subject areas
- Clinical Neurology
- Surgery
Cite this
Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis : case report. / Pozzati, Eugenio; Zucchelli, Mino; Schiavina, Mario; Contini, Paola; Foschini, Maria Pia.
In: Surgical Neurology, Vol. 68, No. 6, 12.2007, p. 671-674.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Rapid growth and regression of intracranial meningiomas in lymphangioleiomyomatosis
T2 - case report
AU - Pozzati, Eugenio
AU - Zucchelli, Mino
AU - Schiavina, Mario
AU - Contini, Paola
AU - Foschini, Maria Pia
PY - 2007/12
Y1 - 2007/12
N2 - Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.
AB - Background: Lymphangioleiomyomatosis is a progressive interstitial lung disease that affects young women. It has been suggested that estrogens play a role in its evolution, and progesterone therapy is often provided in these cases. Case Description: We present a case of a postmenopausal woman with LAM treated with progesterone; subsequently, rapid growth of multiple intracranial meningiomas was observed. One prominent lesion was excised, and 3 other lesions regressed spontaneously over 2 years. Conclusions: This is a rare case of a non-pregnancy-related regression of meningiomas in a woman affected by LAM. The significance of this association and the hormonal treatment of the disease are discussed.
KW - Lymphangioleiomyomatosis
KW - Meningioma
KW - Progesterone
KW - Tuberous sclerosis
UR - http://www.scopus.com/inward/record.url?scp=36448995431&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=36448995431&partnerID=8YFLogxK
U2 - 10.1016/j.surneu.2006.11.063
DO - 10.1016/j.surneu.2006.11.063
M3 - Article
C2 - 17586005
AN - SCOPUS:36448995431
VL - 68
SP - 671
EP - 674
JO - Surgical Neurology
JF - Surgical Neurology
SN - 0090-3019
IS - 6
ER -