Rapid recovery of baroreceptor reflexes in acute myocardial infarction is a marker of effective tissue reperfusion

Gaetano M. De Ferrari, Antonio Sanzo, Grazia Maria Castelli, Annalisa Turco, Alice Ravera, Fabio Badilini, Peter J. Schwartz

Research output: Contribution to journalArticle

Abstract

Baroreflex sensitivity (BRS) measured several days after myocardial infarction (MI) is a powerful predictor of cardiovascular mortality. No information is available on BRS in the early hours of MI. The possibility to reliably assess BRS in the acute phase of MI and its clinical correlates were evaluated in 45 patients treated with primary percutaneous coronary intervention (pPCI). BRS (sequence method) was assessed 1, 3, 6, and 12 h after PCI. ST resolution (STRes) was considered present if ST had decreased ≥70 % 3 h after PCI. BRS was 10.7±6.2 1 h after PCI; at 12 h it was 15.4±5.2 and 8.4±4.8 ms/mmHg in patients with and without STRes, respectively (p

Original languageEnglish
Pages (from-to)553-559
Number of pages7
JournalJournal of Cardiovascular Translational Research
Volume7
Issue number6
DOIs
Publication statusPublished - 2014

Keywords

  • Autonomic nervous system
  • Baroreflex control
  • Myocardial infarction
  • Reperfusion injury
  • Vagal activity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Genetics
  • Genetics(clinical)
  • Molecular Medicine
  • Pharmaceutical Science
  • Medicine(all)

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