Rapidly progressive form of Creutzfeldt-Jakob disease without dementia: A case report

M. G. Marciani, G. Bernardi, G. Sancesario, G. L. Gigli, M. Maschio, G. Palmieri, S. Schiaroli

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We describe a case of a patient with Creutzfeldt-Jakob disease (CJD) characterized by a rapid clinical course lasting one and a half months, by: presence of focal dystonic movements at onset, absence of mental deterioration in the period preceding the impairment of consciousness, ataxia, myoclonus and periodic EEG abnormalities. The autopsy confirmed subacute spongiform encephalopathy, but no evident neuronal loss was observed. An acute clinical course of CJD may explain this latter histological finding which, in turn, probably provides an explanation for the absence of intellectual impairment.

Original languageEnglish
Pages (from-to)115-120
Number of pages6
JournalInternational Journal of Neuroscience
Volume84
Issue number1-4
Publication statusPublished - 1996

Fingerprint

Creutzfeldt-Jakob Syndrome
Dementia
Consciousness
Electroencephalography
Autopsy

Keywords

  • Cognitive impairment
  • Creutzfeldt-Jakob disease

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Marciani, M. G., Bernardi, G., Sancesario, G., Gigli, G. L., Maschio, M., Palmieri, G., & Schiaroli, S. (1996). Rapidly progressive form of Creutzfeldt-Jakob disease without dementia: A case report. International Journal of Neuroscience, 84(1-4), 115-120.

Rapidly progressive form of Creutzfeldt-Jakob disease without dementia : A case report. / Marciani, M. G.; Bernardi, G.; Sancesario, G.; Gigli, G. L.; Maschio, M.; Palmieri, G.; Schiaroli, S.

In: International Journal of Neuroscience, Vol. 84, No. 1-4, 1996, p. 115-120.

Research output: Contribution to journalArticle

Marciani, MG, Bernardi, G, Sancesario, G, Gigli, GL, Maschio, M, Palmieri, G & Schiaroli, S 1996, 'Rapidly progressive form of Creutzfeldt-Jakob disease without dementia: A case report', International Journal of Neuroscience, vol. 84, no. 1-4, pp. 115-120.
Marciani MG, Bernardi G, Sancesario G, Gigli GL, Maschio M, Palmieri G et al. Rapidly progressive form of Creutzfeldt-Jakob disease without dementia: A case report. International Journal of Neuroscience. 1996;84(1-4):115-120.
Marciani, M. G. ; Bernardi, G. ; Sancesario, G. ; Gigli, G. L. ; Maschio, M. ; Palmieri, G. ; Schiaroli, S. / Rapidly progressive form of Creutzfeldt-Jakob disease without dementia : A case report. In: International Journal of Neuroscience. 1996 ; Vol. 84, No. 1-4. pp. 115-120.
@article{d4c95712a9954879bd90d80d80753abe,
title = "Rapidly progressive form of Creutzfeldt-Jakob disease without dementia: A case report",
abstract = "We describe a case of a patient with Creutzfeldt-Jakob disease (CJD) characterized by a rapid clinical course lasting one and a half months, by: presence of focal dystonic movements at onset, absence of mental deterioration in the period preceding the impairment of consciousness, ataxia, myoclonus and periodic EEG abnormalities. The autopsy confirmed subacute spongiform encephalopathy, but no evident neuronal loss was observed. An acute clinical course of CJD may explain this latter histological finding which, in turn, probably provides an explanation for the absence of intellectual impairment.",
keywords = "Cognitive impairment, Creutzfeldt-Jakob disease",
author = "Marciani, {M. G.} and G. Bernardi and G. Sancesario and Gigli, {G. L.} and M. Maschio and G. Palmieri and S. Schiaroli",
year = "1996",
language = "English",
volume = "84",
pages = "115--120",
journal = "International Journal of Neuroscience",
issn = "0020-7454",
publisher = "Informa Healthcare",
number = "1-4",

}

TY - JOUR

T1 - Rapidly progressive form of Creutzfeldt-Jakob disease without dementia

T2 - A case report

AU - Marciani, M. G.

AU - Bernardi, G.

AU - Sancesario, G.

AU - Gigli, G. L.

AU - Maschio, M.

AU - Palmieri, G.

AU - Schiaroli, S.

PY - 1996

Y1 - 1996

N2 - We describe a case of a patient with Creutzfeldt-Jakob disease (CJD) characterized by a rapid clinical course lasting one and a half months, by: presence of focal dystonic movements at onset, absence of mental deterioration in the period preceding the impairment of consciousness, ataxia, myoclonus and periodic EEG abnormalities. The autopsy confirmed subacute spongiform encephalopathy, but no evident neuronal loss was observed. An acute clinical course of CJD may explain this latter histological finding which, in turn, probably provides an explanation for the absence of intellectual impairment.

AB - We describe a case of a patient with Creutzfeldt-Jakob disease (CJD) characterized by a rapid clinical course lasting one and a half months, by: presence of focal dystonic movements at onset, absence of mental deterioration in the period preceding the impairment of consciousness, ataxia, myoclonus and periodic EEG abnormalities. The autopsy confirmed subacute spongiform encephalopathy, but no evident neuronal loss was observed. An acute clinical course of CJD may explain this latter histological finding which, in turn, probably provides an explanation for the absence of intellectual impairment.

KW - Cognitive impairment

KW - Creutzfeldt-Jakob disease

UR - http://www.scopus.com/inward/record.url?scp=0030075697&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030075697&partnerID=8YFLogxK

M3 - Article

C2 - 8707472

AN - SCOPUS:0030075697

VL - 84

SP - 115

EP - 120

JO - International Journal of Neuroscience

JF - International Journal of Neuroscience

SN - 0020-7454

IS - 1-4

ER -