Rapidly progressive squamous cell carcinoma of the cervix coexisting with human immunodeficiency virus infection

Clinical opinion

Lisa Barrie Schwartz, Maria Louisa Carcangiu, Laura Bradham, Peter E. Schwartz

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

The acquired immune deficiency syndrome (AIDS) has been characterized by aggressive malignancies and infections with unusual presentations. There is a well-documented association between cervical dysplasia and the development of cervical carcinoma, and more recent evidence of an association between cervical dysplasia and HIV infection. The course of coexistent HIV infection and cervical cancer has not been well described. We report a patient with HIV infection and a stage IIIB squamous cell carcinoma of the cervix who, despite adequate treatment, had rapid disease progression as well as metastasis to an unusual iliopsoas muscle site in association with an abscess. As HIV becomes more prevalent in the female population, an increased frequency of rapidly progressive cervical carcinoma may be forthcoming. Improved life expectancy of HIV-infected patients due to modern medication is anticipated, causing a cervical neoplasm to have a more prominent effect on prognosis. Close surveillance with frequent Pap smears and colposcopies as well as aggressive management of cervical dysplasia and carcinoma in HIV-infected patients is suggested as is thorough patient counseling.

Original languageEnglish
Pages (from-to)255-258
Number of pages4
JournalGynecologic Oncology
Volume41
Issue number3
DOIs
Publication statusPublished - 1991

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Virus Diseases
Uterine Cervical Dysplasia
Cervix Uteri
Squamous Cell Carcinoma
HIV
HIV Infections
Carcinoma
Uterine Cervical Neoplasms
Papanicolaou Test
Colposcopy
Life Expectancy
Abscess
Disease Progression
Counseling
Acquired Immunodeficiency Syndrome
Neoplasm Metastasis
Muscles
Infection
Population
Neoplasms

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Oncology

Cite this

Rapidly progressive squamous cell carcinoma of the cervix coexisting with human immunodeficiency virus infection : Clinical opinion. / Schwartz, Lisa Barrie; Carcangiu, Maria Louisa; Bradham, Laura; Schwartz, Peter E.

In: Gynecologic Oncology, Vol. 41, No. 3, 1991, p. 255-258.

Research output: Contribution to journalArticle

Schwartz, Lisa Barrie ; Carcangiu, Maria Louisa ; Bradham, Laura ; Schwartz, Peter E. / Rapidly progressive squamous cell carcinoma of the cervix coexisting with human immunodeficiency virus infection : Clinical opinion. In: Gynecologic Oncology. 1991 ; Vol. 41, No. 3. pp. 255-258.
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