Rat dopaminergic function in the retina during aging

F. Riccardi, V. Covelli, P. F. Spano, S. Govoni, M. Trabucchi

Research output: Contribution to journalArticlepeer-review

Abstract

Parameters of dopaminergic transmission were studied in the retina of mature (3-4 months) and aged (23-24 months) rats. In the retina of senescent rats we found significantly higher dihydroxyphenylacetic acid (DOPAC) levels and a higher number of (3H)-spiroperidol binding sites. We detected also an increase of (3H)-methionine-enkephalin binding sites. The changes in the density of (3H)-spiroperidol and (3H)-Metenkephalin binding sites in the retina are opposite to those observed in the brain of aged rats.

Original languageEnglish
Pages (from-to)229-231
Number of pages3
JournalNeurobiology of Aging
Volume2
Issue number3
DOIs
Publication statusPublished - 1981

Keywords

  • Aging
  • Dopamine
  • Retina

ASJC Scopus subject areas

  • Clinical Neurology
  • Biological Psychiatry
  • Developmental Neuroscience
  • Neurology
  • Psychology(all)

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