Rates of Positive Surgical Margins and Their Effect on Cancer-specific Mortality at Radical Prostatectomy for Patients With Clinically Localized Prostate Cancer

Felix Preisser, Elio Mazzone, Sophie Knipper, Sebastiano Nazzani, Marco Bandini, Shahrokh F. Shariat, Zhe Tian, Fred Saad, Francesco Montorsi, Kevin C. Zorn, Markus Graefen, Derya Tilki, Pierre I. Karakiewicz

Research output: Contribution to journalArticle

Abstract

Positive surgical margins (PSM) represent a quality of care indicator at radical prostatectomy. Within the Surveillance, Epidemiology, and End Results (SEER) database, we analyzed PSM trends. We recorded a significant in PSM rates in the overall population, as well as in pathologic stages (pT2 vs. pT3a). Lack of specific information on PSM focality, length, and association with Gleason score undermines the ability to fully explain some of our observations.

Original languageEnglish
Pages (from-to)e130-e139
JournalClinical Genitourinary Cancer
Volume17
Issue number1
DOIs
Publication statusPublished - Feb 2019

Keywords

  • Cancer specific mortality
  • Prostate cancer
  • Radical prostatectomy
  • SEER database
  • Surgical margin

ASJC Scopus subject areas

  • Oncology
  • Urology

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    Preisser, F., Mazzone, E., Knipper, S., Nazzani, S., Bandini, M., Shariat, S. F., Tian, Z., Saad, F., Montorsi, F., Zorn, K. C., Graefen, M., Tilki, D., & Karakiewicz, P. I. (2019). Rates of Positive Surgical Margins and Their Effect on Cancer-specific Mortality at Radical Prostatectomy for Patients With Clinically Localized Prostate Cancer. Clinical Genitourinary Cancer, 17(1), e130-e139. https://doi.org/10.1016/j.clgc.2018.09.024