Rathke's cleft cyst: A clinical and radiographic review

Luigi Cervoni, M. Artico, M. Salvati, S. Carloia

Research output: Contribution to journalArticlepeer-review


We report the case of a 62-year-old woman, who had a 4-year history of progressive visual acuity deficit. On neurological examination, visual acuity was 5/20 in the right and 4/20 in the left eye. A hormonal study revealed hypophyseal hypofunction. CT and MRI scans showed an intra-suprasellar cystic lesion, hyperintense in Tl and hyperintense in T2-weighted sequences. At surgery, the cyst wall was opened and the cavity placed in communication with the subarachnoid space. Histological examination showed a Rathke's cleft cyst. After four years of follow-up the patient's visual deficit remained unchanged, whereas the results of the hormonal assays were normal. An MRI scan confirmed the absence of the cyst. We review 216 reported cases of Rathke's cyst and discuss its pathogenesis, clinical features and treatment.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalNeurological Sciences
Issue number1
Publication statusPublished - 1997


  • Pituitary cyst
  • Rathke's cleft cyst

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology
  • Neuroscience(all)


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