Rationale and design of the health economics evaluation registry for remote follow-up: TARIFF

Renato P. Ricci, Antonio D'Onofrio, Luigi Padeletti, Antonio Sagone, Alfredo Vicentini, Antonio Vincenti, Loredana Morichelli, Ciro Cavallaro, Giuseppe Ricciardi, Leonida Lombardi, Antonio Fusco, Giovanni Rovaris, Paolo Silvestri, Tiziana Guidotto, Annalisa Pollastrelli, Massimo Santini

Research output: Contribution to journalArticlepeer-review


AimsThe aims of the study are to develop a cost-minimization analysis from the hospital perspective and a cost-effectiveness analysis from the third payer standpoint, based on direct estimates of costs and QOL associated with remote follow-ups, using Merlinhome and Merlin.net, compared with standard ambulatory follow-ups, in the management of ICD and CRT-D recipients.Methods and resultsRemote monitoring systems can replace ambulatory follow-ups, sparing human and economic resources, and increasing patient safety. TARIFF is a prospective, controlled, observational study aimed at measuring the direct and indirect costs and quality of life (QOL) of all participants by a 1-year economic evaluation. A detailed set of hospitalized and ambulatory healthcare costs and losses of productivity that could be directly influenced by the different means of follow-ups will be collected. The study consists of two phases, each including 100 patients, to measure the economic resources consumed during the first phase, associated with standard ambulatory follow-ups, vs. the second phase, associated with remote follow-ups.ConclusionRemote monitoring systems enable caregivers to better ensure patient safety and the healthcare to limit costs. TARIFF will allow defining the economic value of remote ICD follow-ups for Italian hospitals, third payers, and patients. The TARIFF study, based on a cost-minimization analysis, directly comparing remote follow-up with standard ambulatory visits, will validate the cost effectiveness of the Merlin.net technology, and define a proper reimbursement schedule applicable for the Italian healthcare system.Trial registration: NCT01075516.

Original languageEnglish
Pages (from-to)1661-1665
Number of pages5
Issue number11
Publication statusPublished - Nov 2012


  • Cardiac resynchronization therapy
  • Implantable cardioverter defibrillator
  • Remote monitoring
  • Telemedicine
  • Telemonitoring

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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