Razionale, disegno e metodi del CTCA-PRORECAD (Registro di Prognosi per la Malattia delle Arterie Coronarie mediante Angiografia Coronarica a Tomografia Computerizzata); un registro multi-centrico e multi-vendor

Translated title of the contribution: Rationale, design and methods of CTCA-PRORECAD (Computed Tomography Coronary Angiography Prognostic Registry for Coronary Artery Disease): A multicentre and multivendor registry

E. Maffei, M. Midiri, V. Russo, M. Rengo, C. Tedeschi, P. Spagnolo, S. Seitun, M. Francone, A. I. Guaricci, N. Carrabba, R. Malagò, A. Cuocolo, T. Arcadi, O. A. Catalano, F. Cademartiri

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose: This study was done to assess the prognostic value of computed tomography coronary angiography (CTCA) in a large multicentre population of patients with suspected coronary artery disease (CAD) and, in particular, its incremental value compared with traditional methods for risk stratification. Materials and methods: This is a retrospective observational study that began in January 2003 conducted on patients with suspected CAD assessed with CTCA on the basis of symptoms (chest pain, dyspnoea) and/or abnormal or equivocal stress test and/or a high cardiovascular risk profile. The participating centres will provide data obtained with CTCA performed with 16-slice or higher equipment. Exclusion criteria are renal insufficiency, allergy to iodinated contrast material, pregnancy and previous myocardial infarction or revascularisation (percutaneous coronary intervention and/or coronary artery bypass graft). All patients are stratified by means of clinical assessment and/or data retrieved from a clinical database. Risk factors considered are hypertension, dyslipidaemia, diabetes mellitus, smoking, family history and obesity. Symptoms are classified as absent, typical chest pain, atypical chest pain and dyspnoea. Primary endpoints are death, major adverse cardiovascular events (cardiac death, unstable angina requiring hospitalisation, acute myocardial infarction) and shifting of cardiovascular risk category on the basis of coronary plaque burden. The secondary endpoint is coronary revascularisation. Telephone interviews and/or clinical databases are used for the follow-up. The study will be conducted on a population >1,000 patients. Conclusions: The information collected from the Prognostic Registry for Coronary Artery Disease (PRORECAD) will provide insight into the prognostic value of CTCA in addition to demographic and clinical features. The results will allow for better use and interpretation of CTCA for prognostic purposes.

Original languageItalian
Pages (from-to)591-607
Number of pages17
JournalRadiologia Medica
Volume118
Issue number4
DOIs
Publication statusPublished - Jun 2013

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Coronary Angiography
Registries
Coronary Artery Disease
Chest Pain
Dyspnea
Myocardial Infarction
Databases
Myocardial Revascularization
Unstable Angina
Percutaneous Coronary Intervention
Dyslipidemias
Exercise Test
Coronary Artery Bypass
Contrast Media
Population
Observational Studies
Renal Insufficiency
Diabetes Mellitus
Hypersensitivity
Hospitalization

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Razionale, disegno e metodi del CTCA-PRORECAD (Registro di Prognosi per la Malattia delle Arterie Coronarie mediante Angiografia Coronarica a Tomografia Computerizzata); un registro multi-centrico e multi-vendor. / Maffei, E.; Midiri, M.; Russo, V.; Rengo, M.; Tedeschi, C.; Spagnolo, P.; Seitun, S.; Francone, M.; Guaricci, A. I.; Carrabba, N.; Malagò, R.; Cuocolo, A.; Arcadi, T.; Catalano, O. A.; Cademartiri, F.

In: Radiologia Medica, Vol. 118, No. 4, 06.2013, p. 591-607.

Research output: Contribution to journalArticle

Maffei, E, Midiri, M, Russo, V, Rengo, M, Tedeschi, C, Spagnolo, P, Seitun, S, Francone, M, Guaricci, AI, Carrabba, N, Malagò, R, Cuocolo, A, Arcadi, T, Catalano, OA & Cademartiri, F 2013, 'Razionale, disegno e metodi del CTCA-PRORECAD (Registro di Prognosi per la Malattia delle Arterie Coronarie mediante Angiografia Coronarica a Tomografia Computerizzata); un registro multi-centrico e multi-vendor', Radiologia Medica, vol. 118, no. 4, pp. 591-607. https://doi.org/10.1007/s11547-012-0912-9
Maffei, E. ; Midiri, M. ; Russo, V. ; Rengo, M. ; Tedeschi, C. ; Spagnolo, P. ; Seitun, S. ; Francone, M. ; Guaricci, A. I. ; Carrabba, N. ; Malagò, R. ; Cuocolo, A. ; Arcadi, T. ; Catalano, O. A. ; Cademartiri, F. / Razionale, disegno e metodi del CTCA-PRORECAD (Registro di Prognosi per la Malattia delle Arterie Coronarie mediante Angiografia Coronarica a Tomografia Computerizzata); un registro multi-centrico e multi-vendor. In: Radiologia Medica. 2013 ; Vol. 118, No. 4. pp. 591-607.
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AU - Maffei, E.

AU - Midiri, M.

AU - Russo, V.

AU - Rengo, M.

AU - Tedeschi, C.

AU - Spagnolo, P.

AU - Seitun, S.

AU - Francone, M.

AU - Guaricci, A. I.

AU - Carrabba, N.

AU - Malagò, R.

AU - Cuocolo, A.

AU - Arcadi, T.

AU - Catalano, O. A.

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N2 - Purpose: This study was done to assess the prognostic value of computed tomography coronary angiography (CTCA) in a large multicentre population of patients with suspected coronary artery disease (CAD) and, in particular, its incremental value compared with traditional methods for risk stratification. Materials and methods: This is a retrospective observational study that began in January 2003 conducted on patients with suspected CAD assessed with CTCA on the basis of symptoms (chest pain, dyspnoea) and/or abnormal or equivocal stress test and/or a high cardiovascular risk profile. The participating centres will provide data obtained with CTCA performed with 16-slice or higher equipment. Exclusion criteria are renal insufficiency, allergy to iodinated contrast material, pregnancy and previous myocardial infarction or revascularisation (percutaneous coronary intervention and/or coronary artery bypass graft). All patients are stratified by means of clinical assessment and/or data retrieved from a clinical database. Risk factors considered are hypertension, dyslipidaemia, diabetes mellitus, smoking, family history and obesity. Symptoms are classified as absent, typical chest pain, atypical chest pain and dyspnoea. Primary endpoints are death, major adverse cardiovascular events (cardiac death, unstable angina requiring hospitalisation, acute myocardial infarction) and shifting of cardiovascular risk category on the basis of coronary plaque burden. The secondary endpoint is coronary revascularisation. Telephone interviews and/or clinical databases are used for the follow-up. The study will be conducted on a population >1,000 patients. Conclusions: The information collected from the Prognostic Registry for Coronary Artery Disease (PRORECAD) will provide insight into the prognostic value of CTCA in addition to demographic and clinical features. The results will allow for better use and interpretation of CTCA for prognostic purposes.

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KW - Computed tomography coronary angiography

KW - Coronary artery disease

KW - Prevalence of disease

KW - Prognosis

KW - Registry

KW - Risk stratification

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