TY - JOUR
T1 - RDW
T2 - Nuovo test per lo screening del morbo celiaco?
AU - Guglielmi, V.
AU - Manchisi, M.
AU - Pellegrini, V.
AU - Tutino, M.
AU - Guerra, V.
PY - 2002/10
Y1 - 2002/10
N2 - Background. Notwithstanding the presence of numerous examinations for screening coeliac disease, it may still escape timely diagnosis. For this reason we carried out an investigation to see whether simple haemato-chemical anomalies (as revealed in what are now routine examinations carried out during hospitalisation) might make diagnosis quicker or at least trigger the suspicion of coeliac disease. Methods. Retrospectively, of 21 adult patients admitted to our hospital for the first time and who were diagnosed with coeliac disease, we considered haemoglobin, iron, calcium, potassium, albumin and RDW (part of the normal blood count). Results. We found that elevated RDW was the most frequent anomaly (67% of patients) of the six haematochemical parameters observed. In addition, it became normal in most patients after a gluten-free diet. Conclusions. Elevated RDW was more frequent than sideropenic anaemia in patients with coeliac disease. In addition, RDW indicates a response to diet therapy because it became normal after a gluten-free diet.
AB - Background. Notwithstanding the presence of numerous examinations for screening coeliac disease, it may still escape timely diagnosis. For this reason we carried out an investigation to see whether simple haemato-chemical anomalies (as revealed in what are now routine examinations carried out during hospitalisation) might make diagnosis quicker or at least trigger the suspicion of coeliac disease. Methods. Retrospectively, of 21 adult patients admitted to our hospital for the first time and who were diagnosed with coeliac disease, we considered haemoglobin, iron, calcium, potassium, albumin and RDW (part of the normal blood count). Results. We found that elevated RDW was the most frequent anomaly (67% of patients) of the six haematochemical parameters observed. In addition, it became normal in most patients after a gluten-free diet. Conclusions. Elevated RDW was more frequent than sideropenic anaemia in patients with coeliac disease. In addition, RDW indicates a response to diet therapy because it became normal after a gluten-free diet.
KW - Celiac disease, diagnosis
KW - Celiac disease, diet therapy
KW - Celiac disease, immunology
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M3 - Articolo
C2 - 12410174
AN - SCOPUS:0036818431
VL - 93
SP - 419
EP - 421
JO - Minerva Medicolegale e Archivio di Antropologia Criminale
JF - Minerva Medicolegale e Archivio di Antropologia Criminale
SN - 0026-4806
IS - 5
ER -