Intrahepatic recurrence after curative liver resection is a common event. In the last 15 years, the rate of re-resection of a liver recurrence has progressively increased such that up to 20% of patients with an intrahepatic recurrence are now expected to undergo re-resection. Although re-resection is technically more demanding, mortality/morbidity and long-term survival rates are similar to those reported for initial liver resection. The major indication for re-resection is the technical feasibility of a curative procedure.
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