Reaction of 2-amino-2-deoxy-d-glucose and lysine: Isolation and characterization of 2,5-bis(tetrahydroxybutyl)pyrazine

Giovanni Candiano, Gian Marco Ghiggeri, Rosanna Gusmano, Lucia Zetta, Emilio Benfenati, Giorgio Icardi

Research output: Contribution to journalArticle

Abstract

The reaction of 2-amino-2-deoxy-d-glucose with lysine in water under simulated physiological conditions gave several browning products, with characteristic optical (λmax 340 nm) and fluorescent properties (emission at 430 nm for excitation at 362 nm). The major product was isolated and characterized by mass spectrometry and n.m.r. spectroscopy as 2,5-bis(tetrahydroxybutyl)pyrazine derived by the condensation of two molecules of 2-amino-2-deoxy-d-glucose.

Original languageEnglish
Pages (from-to)67-75
Number of pages9
JournalCarbohydrate Research
Volume184
Issue numberC
DOIs
Publication statusPublished - Dec 31 1988

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Organic Chemistry

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