Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria

F. Tedesco, R. Corrocher, E. Jirillo, G. De Sandre

Research output: Contribution to journalArticle

Abstract

The sensitivity to the reactive lysis of normal, PNH and PNH like cells was studied and quantitated either on agarose plates or spectrophotometrically. The PNH and PNH like cells are particularly sensitive in this haemolytic system which represents, for this reason, a new diagnostic method for PNH. Since the AR (C5-C6 complex) was found in a PNH patient, the possible role of this alternative complement pathway in triggering the haemolytic crisis in these patients is discussed.

Original languageEnglish
Pages (from-to)292-297
Number of pages6
JournalHaematologica
Volume59
Issue number3
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Hematology

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    Tedesco, F., Corrocher, R., Jirillo, E., & De Sandre, G. (1974). Reactive haemolysis test in paroxysmal nocturnal haemoglobinuria. Haematologica, 59(3), 292-297.