Il disturbo di lettura nei pazienti con epilessia farmaco-resistente (EFFR)

Translated title of the contribution: Reading disorder in children with drug-resistant focal epilepsy

I. Derada Troletti, L. Danelli, P. Scarpa, S. Francione, G. Lo Russo, E. Paulesu, G. Bottini

Research output: Contribution to journalArticle

Abstract

Children with epilepsy, especially those with drug-resistant focal epilepsy, appear to be particularly exposed to the risk of developing learning disabilities, such as dyslexia. However it is not always clear what type of neuropsychological profile is associated to the reading deficiency in this population and which clinical variables are involved in its etiology. In the following retrospective study we compared the performance observed in several cognitive tasks of two groups of 13 children with drug-resistant focal epilepsy, one with and one without reading disability, before and six months after surgery. Furthermore, in order to investigate which factors were involved in the etiology of dyslexia, we compared the two groups with respect to some clinical variables. The results showed a globally impaired cognitive profile among children with reading disability, as compared to that of children without reading disability, both before and after surgery. Even though both groups tended to maintain stability in almost every cognitive domain at six months after surgery, children with and without dyslexia showed a significant improvement in a few areas of cognition more pronounced in subject without reading disabilities. Finally, with respect to clinical variables, our results showed that the presence of dyslexia was more likely associated with an earlier onset and longer duration of epilepsy and furthermore, it was more likely to occur in children suffering from epilepsy due to malformations of cortical development. These results suggest that reading disabilities in children with drug-resistant focal epilepsy are generally associated with a more severe clinical and cognitive profile.

Translated title of the contributionReading disorder in children with drug-resistant focal epilepsy
Original languageItalian
Pages (from-to)240-242
Number of pages3
JournalBollettino - Lega Italiana contro l'Epilessia
Issue number145
Publication statusPublished - Apr 2013

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Derada Troletti, I., Danelli, L., Scarpa, P., Francione, S., Lo Russo, G., Paulesu, E., & Bottini, G. (2013). Il disturbo di lettura nei pazienti con epilessia farmaco-resistente (EFFR). Bollettino - Lega Italiana contro l'Epilessia, (145), 240-242.