Ruolo dell'elastosonografia prostatica transrettale nella diagnostica per immagini del carcinoma prostatico: esperienza personale.

Translated title of the contribution: [Real-time elastography in the diagnosis of prostate cancer: personal experience].

Andrea Romagnoli, Gaspare Autieri, Danilo Centrella, Christian Gastaldi, Giuseppe Pedaci, Lorenzo Rivolta, Emilio Pozzi, Alessio Anghileri, Maurizio Cerabino, Carlo Maria Bianchi, Alberto Roggia

Research output: Contribution to journalArticlepeer-review

Abstract

Prostate cancer is the most common cancer in men. In the future, a significant further increase in the incidence of prostate cancer is expected. The indication to perform a prostate biopsy is digital rectal examination suspicious for prostate cancer, total prostate specific antigen (PSA) value, free PSA/total PSA ratio, PSA density and PSA velocity, and an evidence of hypoechoic area at transrectal ultrasound scan. Unfortunately the specificity and sensibility are still poor. The aim of this retrospective study is to evaluate the specificity and sensibility of real time elastography versus ultrasound transrectal B-mode scan. We retrospectively evaluated 108 pts. having undergone TRUS-guided transrectal prostate biopsy (10 samples). The indication for biopsy is: digital rectal examination, total prostate specific antigen (PSA) value, PSA ratio, PSA density and PSA velocity suspicious for prostate cancer, and/or an evidence of hypoechoic area at transrectal ultrasound scan, and/or hard area at real-time elastography. The mean age of patients is 66.8 years, mean PSA 6.5 ng/mL, and mean ratio 16.5%. We compared the histopathological findings of needle prostate biopsies with the results of transrectal ultrasound and transrectal real-time elastography. 32/108 (29.6%) pts. were positive for prostate cancer (mean Gleason score 7.08), mean PSA 14 ng/mL and mean ratio 9.5%. Transrectal ultrasound scan shows a sensibility of 69% and specificity of 68%. Transrectal ultrasound scan shows a VPP of 51.4%. Transrectal ultrasound scan shows a VPN of 80.9%. Real-time elastography shows a sensibility of 56% and specificity of 85.7%. Real-time elastography shows a VPP of 60.1%. Real-time elastography shows a VPN of 83%. Elastography has a significantly higher specificity for the detection of prostate cancer than the conventionally used examinations including DRE and TRUS. It is a useful real-time diagnostic method because it is not invasive, and simultaneous evaluation is possible while performing TRUS.

Translated title of the contribution[Real-time elastography in the diagnosis of prostate cancer: personal experience].
Original languageItalian
Pages (from-to)248-253
Number of pages6
JournalUrologia
Volume77
Issue number4
Publication statusPublished - Oct 2010

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of '[Real-time elastography in the diagnosis of prostate cancer: personal experience].'. Together they form a unique fingerprint.

Cite this