Reasons why COVID-19 survivors should follow dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) recommendations: From hyper-inflammation to cardiac dysfunctions

V. Quagliariello, G. D’Aiuto, R. V. Iaffaioli, M. Berretta, S. Buccolo, M. Iovine, A. Paccone, F. Cerrone, S. Bonanno, G. Nunnari, N. Laganà, G. Botti, N. Maurea

Research output: Contribution to journalArticlepeer-review

Abstract

The World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) advise cancer survivors to follow their lifestyle recommendations for cancer prevention. Recent research indicates that a proper diet could exerts beneficial metabolic and immune effects in humans through the involvement of several, not yet properly known, metabolic pathways. Here, we argue that following WCRF/AICR recommendations could be a strategy to prevent cardiovascular outcomes [fulminant myocarditis, heart failure, venous thromboembolism (VTE)] and acute respiratory distress syndrome (ARDS) in patients during follow-up post COVID-19 infection. We discuss the metabolic effects of a WCRF/AICR based diet, highlighting on the involved cardio-metabolic pathways related on NLRP3 inflammasome-cytokines axis aimed to improve prognosis of COVID-19, especially in patients with cancer.

Original languageEnglish
Pages (from-to)3898-3907
Number of pages10
JournalEuropean Review for Medical and Pharmacological Sciences
Volume25
Issue number10
DOIs
Publication statusPublished - 2021

Keywords

  • Cancer
  • Cardio - oncology
  • COVID -19
  • Diet
  • Nutrition

ASJC Scopus subject areas

  • Pharmacology (medical)

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