Abstract
The very low sensitivity of Scintimammography for tumors under 1 cm in diameter, with current nuclear medicine cameras in use, is the major limitation in recommending this test modality for screening purposes. Recently latest generation cameras with superior imaging performances have allowed to foresee a very promising future for scintimammography. Recent technological advances obtained from our research group on the new Lanthanum scintillation crystals are now demonstrating how continuous crystals coupled to Hamamatsu Flat panel tube can overcome a number of limitations in spatial and energy resolution of scintillation arrays, carrying out 6% energy resolution, and submillimeter spatial resolution values at 140 keV. In this paper three basic detection systems have been analysed: a LumaGEM 3200S gamma camera (Gamma Medica, InC., Northridge, USA), based on a cadmium-zinc-telluride (CZT) semiconductor detector with a FoV of 12.5×12.5 cm2 and with detector elements of 1.6×1.6 mm2 in size and a detector prototype consisting of a Flat panel PMT coupled to planar LaBr3:Ce scintillator. The third one is a first generation large FoV gamma camera chosen for comparison, based on PSPMTs photodetector array coupled to a NaI(Tl) scintillation crystal matrix. LaBr3:Ce and CZT cameras showed superior spatial and energy resolution than previous generation one based on NaI(Tl) scintillation array. Both CZT and LaBr gamma cameras showed similar efficiencies for the same energy window though LaBr3:Ce continuous crystal showed better imaging performance than pixellated detectors. However large area LaBr3:Ce continuous crystals are not available yet.
| Original language | English |
|---|---|
| Pages (from-to) | 296-300 |
| Number of pages | 5 |
| Journal | Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment |
| Volume | 569 |
| Issue number | 2 SPEC. ISS. |
| DOIs | |
| Publication status | Published - Dec 20 2006 |
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Keywords
- CZT
- Gamma-ray imagers
- Lanthanum bromide
- Nuclear medicine
- Scintimammography
ASJC Scopus subject areas
- Instrumentation
- Nuclear and High Energy Physics
Cite this
Recent advances and future perspectives of gamma imagers for scintimammography. / Pani, R.; Pellegrini, R.; Cinti, M. N.; Bennati, P.; Betti, M.; Casali, V.; Schillaci, O.; Mattioli, M.; Orsolini Cencelli, V.; Navarria, F.; Bollini, D.; Moschini, G.; Garibaldi, F.; Cusanno, F.; Iurlaro, G.; Montani, L.; Scafè, R.; de Notaristefani, F.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 569, No. 2 SPEC. ISS., 20.12.2006, p. 296-300.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recent advances and future perspectives of gamma imagers for scintimammography
AU - Pani, R.
AU - Pellegrini, R.
AU - Cinti, M. N.
AU - Bennati, P.
AU - Betti, M.
AU - Casali, V.
AU - Schillaci, O.
AU - Mattioli, M.
AU - Orsolini Cencelli, V.
AU - Navarria, F.
AU - Bollini, D.
AU - Moschini, G.
AU - Garibaldi, F.
AU - Cusanno, F.
AU - Iurlaro, G.
AU - Montani, L.
AU - Scafè, R.
AU - de Notaristefani, F.
PY - 2006/12/20
Y1 - 2006/12/20
N2 - The very low sensitivity of Scintimammography for tumors under 1 cm in diameter, with current nuclear medicine cameras in use, is the major limitation in recommending this test modality for screening purposes. Recently latest generation cameras with superior imaging performances have allowed to foresee a very promising future for scintimammography. Recent technological advances obtained from our research group on the new Lanthanum scintillation crystals are now demonstrating how continuous crystals coupled to Hamamatsu Flat panel tube can overcome a number of limitations in spatial and energy resolution of scintillation arrays, carrying out 6% energy resolution, and submillimeter spatial resolution values at 140 keV. In this paper three basic detection systems have been analysed: a LumaGEM 3200S gamma camera (Gamma Medica, InC., Northridge, USA), based on a cadmium-zinc-telluride (CZT) semiconductor detector with a FoV of 12.5×12.5 cm2 and with detector elements of 1.6×1.6 mm2 in size and a detector prototype consisting of a Flat panel PMT coupled to planar LaBr3:Ce scintillator. The third one is a first generation large FoV gamma camera chosen for comparison, based on PSPMTs photodetector array coupled to a NaI(Tl) scintillation crystal matrix. LaBr3:Ce and CZT cameras showed superior spatial and energy resolution than previous generation one based on NaI(Tl) scintillation array. Both CZT and LaBr gamma cameras showed similar efficiencies for the same energy window though LaBr3:Ce continuous crystal showed better imaging performance than pixellated detectors. However large area LaBr3:Ce continuous crystals are not available yet.
AB - The very low sensitivity of Scintimammography for tumors under 1 cm in diameter, with current nuclear medicine cameras in use, is the major limitation in recommending this test modality for screening purposes. Recently latest generation cameras with superior imaging performances have allowed to foresee a very promising future for scintimammography. Recent technological advances obtained from our research group on the new Lanthanum scintillation crystals are now demonstrating how continuous crystals coupled to Hamamatsu Flat panel tube can overcome a number of limitations in spatial and energy resolution of scintillation arrays, carrying out 6% energy resolution, and submillimeter spatial resolution values at 140 keV. In this paper three basic detection systems have been analysed: a LumaGEM 3200S gamma camera (Gamma Medica, InC., Northridge, USA), based on a cadmium-zinc-telluride (CZT) semiconductor detector with a FoV of 12.5×12.5 cm2 and with detector elements of 1.6×1.6 mm2 in size and a detector prototype consisting of a Flat panel PMT coupled to planar LaBr3:Ce scintillator. The third one is a first generation large FoV gamma camera chosen for comparison, based on PSPMTs photodetector array coupled to a NaI(Tl) scintillation crystal matrix. LaBr3:Ce and CZT cameras showed superior spatial and energy resolution than previous generation one based on NaI(Tl) scintillation array. Both CZT and LaBr gamma cameras showed similar efficiencies for the same energy window though LaBr3:Ce continuous crystal showed better imaging performance than pixellated detectors. However large area LaBr3:Ce continuous crystals are not available yet.
KW - CZT
KW - Gamma-ray imagers
KW - Lanthanum bromide
KW - Nuclear medicine
KW - Scintimammography
UR - http://www.scopus.com/inward/record.url?scp=33751547473&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33751547473&partnerID=8YFLogxK
U2 - 10.1016/j.nima.2006.08.024
DO - 10.1016/j.nima.2006.08.024
M3 - Article
AN - SCOPUS:33751547473
VL - 569
SP - 296
EP - 300
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
SN - 0168-9002
IS - 2 SPEC. ISS.
ER -