Recent advances in angiogenesis and antiangiogenesis: The neuroblastoma model

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Promising novel antiangiogenic strategies are emerging for the treatment of cancer and the inhibition of angiogenesis might represent a powerful tool as adjuvant therapy of malignant tumors. Over the last fifteen years several reports have been published concerning the relationship between tumor progression and angiogenesis in neuroblastoma in experimental models in vitro and in vivo. Moreover, a high vascular index in neuroblastoma correlates with poor prognosis, suggesting dependence of aggressive tumor growth on active angiogenesis. Here, we present an overview of the most recent advances in antiangiogenesis in neuroblastoma, and describe tumor vascular-targeted preclinical results, as well as future perspectives. Domenico Ribatti (Ed.) All rights reserved -

Original languageEnglish
Title of host publicationRecent Advances in Angiogenesis and Antiangiogenesis
PublisherBentham Science Publishers Ltd.
Pages85-91
Number of pages7
ISBN (Print)9781608056934
DOIs
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Medicine(all)

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