Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells

Federico Bussolino; Francesco Colotta; Elena Bocchietto; Antonella Guglielmetti; Alberto Mantovani

doi:10.1007/BF02592273

Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor: activities on endothelial cells

Federico Bussolino, Francesco Colotta, Elena Bocchietto, Antonella Guglielmetti, Alberto Mantovani

Research output: Contribution to journal › Article › peer-review

Abstract

Granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor were considered as growth and differentiation factors restricted to hematopoietic cells. It was recently found that non-hematopoietic cells, including endothelial cells, respond to these cytokines. In this review we describe their effects on endothelial cells, underlining their role in the behavior and survival of the microenvironment of bone marrow, in the angiogenesis process related to the progression of solid tumors and of vascular tumors, and in the homing of lymphocytes.

Original language	English
Pages (from-to)	8-12
Number of pages	5
Journal	International Journal of Clinical & Laboratory Research
Volume	23
Issue number	1-4
DOIs	https://doi.org/10.1007/BF02592273
Publication status	Published - Dec 1993

Keywords

Angiogenesis
Bone marrow
Endothelium
Granulocyte-colony stimulating factor
Granulocyte-macrophage colony-stimulating factor
Vascular tumor

ASJC Scopus subject areas

Clinical Biochemistry

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10.1007/BF02592273

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Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor : activities on endothelial cells. / Bussolino, Federico; Colotta, Francesco; Bocchietto, Elena; Guglielmetti, Antonella; Mantovani, Alberto.

In: International Journal of Clinical & Laboratory Research, Vol. 23, No. 1-4, 12.1993, p. 8-12.

Research output: Contribution to journal › Article › peer-review

Bussolino, Federico ; Colotta, Francesco ; Bocchietto, Elena ; Guglielmetti, Antonella ; Mantovani, Alberto. / Recent developments in the cell biology of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor : activities on endothelial cells. In: International Journal of Clinical & Laboratory Research. 1993 ; Vol. 23, No. 1-4. pp. 8-12.

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