TY - JOUR
T1 - Recent imaging advancements for lung metastases in children with sarcoma
AU - Facchini, Giancarlo
AU - Ceccarelli, Luca
AU - Tomà, Paolo
AU - Bartoloni, Alessandra
N1 - Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
PY - 2020/12/28
Y1 - 2020/12/28
N2 - In children and adolescents affected by musculoskeletal sarcomas (both soft tissue and bone sarcomas), the presence of lung metastases is a frequent complication, that should be known since the patient's prognosis, management, and treatment depend on it. During the staging phase, the detection of lung metastases should be sensitive and specific, and it should be carried out minimizing the radiation exposure. To face this problem, imaging has reached important goals in recent years, thanks to the development of cone-beam CT or low-dose computed tomography, with some new iterative reconstruction methods, such as Veo and ASIR. Imaging is also fundamental for the possibility to perform lung biopsies under CT guidance, with less morbidity, less time-consuming, and the shorter recovery time, compared to surgical biopsies. Moreover, important results have also been demonstrated in the treatment of lung metastases, thanks to the improvement of new mini-invasive image-guided percutaneous thermal ablation procedures, which proved to be safe and effective also in young patients.
AB - In children and adolescents affected by musculoskeletal sarcomas (both soft tissue and bone sarcomas), the presence of lung metastases is a frequent complication, that should be known since the patient's prognosis, management, and treatment depend on it. During the staging phase, the detection of lung metastases should be sensitive and specific, and it should be carried out minimizing the radiation exposure. To face this problem, imaging has reached important goals in recent years, thanks to the development of cone-beam CT or low-dose computed tomography, with some new iterative reconstruction methods, such as Veo and ASIR. Imaging is also fundamental for the possibility to perform lung biopsies under CT guidance, with less morbidity, less time-consuming, and the shorter recovery time, compared to surgical biopsies. Moreover, important results have also been demonstrated in the treatment of lung metastases, thanks to the improvement of new mini-invasive image-guided percutaneous thermal ablation procedures, which proved to be safe and effective also in young patients.
KW - Child
KW - X-ray computed tomography
KW - ablation techniques
KW - cone-beam computed tomography
KW - neoplasm metastases
KW - sarcoma
U2 - 10.2174/1573405616666201228125657
DO - 10.2174/1573405616666201228125657
M3 - Article
C2 - 33371858
JO - Current Medical Imaging
JF - Current Medical Imaging
SN - 1573-4021
ER -