Receptors for peanut agglutinin on a high percentage of human cord-blood lymphocytes: phenotype characterization of peanut-positive cells

R. Maccario, F. A. Ferrari, S. Siena, M. A. Vitiello, A. Martini, A. G. Siccardi, A. G. Ugazio

Research output: Contribution to journalArticle

Abstract

The results of this study show that a high percentage of human cord-blood lymphocytes bears receptors for peanut agglutinin. Determination of the presence of other lymphocyte markers (E rosettes, membrane immunoglobulins, alpha-naphthyl-acetate esterase, Ia antigens) in the peanut-positive cells indicated that they include both T and B cells. The peanut receptor, also expressed by blast cells of most acute, but not chronic, leukemias, seems to be a marker of immaturity for both T- and B-lymphocyte subsets in man as it is in the mouse.

Original languageEnglish
Pages (from-to)329-337
Number of pages9
JournalThymus
Volume2
Issue number6
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Immunology

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