TY - JOUR
T1 - Receptors for thymosin alpha 1 on mouse thymocytes
AU - Garaci, Cristina Rinaldi
AU - Torrisi, Maria Rosaria
AU - Jezzi, Teresa
AU - Frati, Luigi
AU - Goldstein, Allan L.
AU - Garaci, Enrico
PY - 1985
Y1 - 1985
N2 - Thymosin α1, is able to act in vitro to stimulate T-cell precursors and to induce surface markers. The initial mechanism by which α1 activates T cells could be the binding of α1 to cell membranes. Using a specific anti-α1 antibody and an indirect immunofluorescence procedure it was found that thymosin α1 binds to the surface of a large portion of murine lymphocytes. Furthermore, thymocytes have been fractionated into immature and mature subpopulations by using the peanut agglutinin (PNA) technique. It was found that PNA+, immature cells showed specific receptors for α1 on the cell membrane.
AB - Thymosin α1, is able to act in vitro to stimulate T-cell precursors and to induce surface markers. The initial mechanism by which α1 activates T cells could be the binding of α1 to cell membranes. Using a specific anti-α1 antibody and an indirect immunofluorescence procedure it was found that thymosin α1 binds to the surface of a large portion of murine lymphocytes. Furthermore, thymocytes have been fractionated into immature and mature subpopulations by using the peanut agglutinin (PNA) technique. It was found that PNA+, immature cells showed specific receptors for α1 on the cell membrane.
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U2 - 10.1016/0008-8749(85)90051-6
DO - 10.1016/0008-8749(85)90051-6
M3 - Article
C2 - 3882244
AN - SCOPUS:0021955313
VL - 91
SP - 289
EP - 293
JO - Cellular Immunology
JF - Cellular Immunology
SN - 0008-8749
IS - 1
ER -