Reciprocal inhibition in forearm muscles in patients with essential tremor

B. Mercuri, A. Berardelli, N. Modugno, L. Vacca, S. Ruggieri, M. Manfredi

Research output: Contribution to journalArticlepeer-review


Reciprocal inhibition of the H-reflex in the forearm flexor muscles was studied in 11 patients with essential tremor and in 10 normal controls. Whereas patients and controls had a similar first, disynaptic phase of reciprocal inhibition, patients had a significantly reduced second phase. Patients with more severe functional impairment had more pronounced abnormalities of reciprocal inhibition. Abnormalities of reciprocal inhibition may play a role in the pathophysiology of essential tremor and probably arise from defective suprasegmental control.

Original languageEnglish
Pages (from-to)796-799
Number of pages4
JournalMuscle and Nerve
Issue number6
Publication statusPublished - 1998


  • Essential tremor
  • Reciprocal inhibition
  • Spinal excitability

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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