Abstract
Recognition memory can be supported by both the assessment of the familiarity of an item and by the recollection of the context in which an item was encountered. The neural substrates of these memory processes are controversial. To address these issues we applied repetitive transcranial magnetic stimulation (rTMS) over the right and left dorsolateral prefrontal cortex (DLPFC) of healthy subjects performing a remember/know task. rTMS disrupted familiarity judgments when applied before encoding of stimuli over both right and left DLPFC. rTMS disrupted recollection when applied before encoding of stimuli over the right DLPFC. These findings suggest that the DLPFC plays a critical role in recognition memory based on familiarity as well as recollection.
| Original language | English |
|---|---|
| Pages (from-to) | 23-27 |
| Number of pages | 5 |
| Journal | Behavioural Neurology |
| Volume | 19 |
| Issue number | 1-2 |
| Publication status | Published - 2008 |
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Keywords
- Familiarity
- Prefrontal cortex
- Recognition memory
- Recollection
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Neuroscience(all)
Cite this
Recognition memory and prefrontal cortex : Dissociating recollection and familiarity processes using rTMS. / Turriziani, Patrizia; Oliveri, Massimiliano; Salerno, Silvia; Costanzo, Floriana; Koch, Giacomo; Caltagirone, Carlo; Carlesimo, Giovanni Augusto.
In: Behavioural Neurology, Vol. 19, No. 1-2, 2008, p. 23-27.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recognition memory and prefrontal cortex
T2 - Dissociating recollection and familiarity processes using rTMS
AU - Turriziani, Patrizia
AU - Oliveri, Massimiliano
AU - Salerno, Silvia
AU - Costanzo, Floriana
AU - Koch, Giacomo
AU - Caltagirone, Carlo
AU - Carlesimo, Giovanni Augusto
PY - 2008
Y1 - 2008
N2 - Recognition memory can be supported by both the assessment of the familiarity of an item and by the recollection of the context in which an item was encountered. The neural substrates of these memory processes are controversial. To address these issues we applied repetitive transcranial magnetic stimulation (rTMS) over the right and left dorsolateral prefrontal cortex (DLPFC) of healthy subjects performing a remember/know task. rTMS disrupted familiarity judgments when applied before encoding of stimuli over both right and left DLPFC. rTMS disrupted recollection when applied before encoding of stimuli over the right DLPFC. These findings suggest that the DLPFC plays a critical role in recognition memory based on familiarity as well as recollection.
AB - Recognition memory can be supported by both the assessment of the familiarity of an item and by the recollection of the context in which an item was encountered. The neural substrates of these memory processes are controversial. To address these issues we applied repetitive transcranial magnetic stimulation (rTMS) over the right and left dorsolateral prefrontal cortex (DLPFC) of healthy subjects performing a remember/know task. rTMS disrupted familiarity judgments when applied before encoding of stimuli over both right and left DLPFC. rTMS disrupted recollection when applied before encoding of stimuli over the right DLPFC. These findings suggest that the DLPFC plays a critical role in recognition memory based on familiarity as well as recollection.
KW - Familiarity
KW - Prefrontal cortex
KW - Recognition memory
KW - Recollection
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UR - http://www.scopus.com/inward/citedby.url?scp=42049092772&partnerID=8YFLogxK
M3 - Article
C2 - 18413912
AN - SCOPUS:42049092772
VL - 19
SP - 23
EP - 27
JO - Behavioural Neurology
JF - Behavioural Neurology
SN - 0953-4180
IS - 1-2
ER -