Recognition memory and prefrontal cortex: Dissociating recollection and familiarity processes using rTMS

Patrizia Turriziani; Massimiliano Oliveri; Silvia Salerno; Floriana Costanzo; Giacomo Koch; Carlo Caltagirone; Giovanni Augusto Carlesimo

Recognition memory and prefrontal cortex: Dissociating recollection and familiarity processes using rTMS

Patrizia Turriziani, Massimiliano Oliveri, Silvia Salerno, Floriana Costanzo, Giacomo Koch, Carlo Caltagirone, Giovanni Augusto Carlesimo

Research output: Contribution to journal › Article › peer-review

Abstract

Recognition memory can be supported by both the assessment of the familiarity of an item and by the recollection of the context in which an item was encountered. The neural substrates of these memory processes are controversial. To address these issues we applied repetitive transcranial magnetic stimulation (rTMS) over the right and left dorsolateral prefrontal cortex (DLPFC) of healthy subjects performing a remember/know task. rTMS disrupted familiarity judgments when applied before encoding of stimuli over both right and left DLPFC. rTMS disrupted recollection when applied before encoding of stimuli over the right DLPFC. These findings suggest that the DLPFC plays a critical role in recognition memory based on familiarity as well as recollection.

Original language	English
Pages (from-to)	23-27
Number of pages	5
Journal	Behavioural Neurology
Volume	19
Issue number	1-2
Publication status	Published - 2008

Keywords

Familiarity
Prefrontal cortex
Recognition memory
Recollection

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Neuroscience(all)

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Recognition memory and prefrontal cortex : Dissociating recollection and familiarity processes using rTMS. / Turriziani, Patrizia; Oliveri, Massimiliano; Salerno, Silvia; Costanzo, Floriana ; Koch, Giacomo ; Caltagirone, Carlo ; Carlesimo, Giovanni Augusto.

In: Behavioural Neurology, Vol. 19, No. 1-2, 2008, p. 23-27.

Research output: Contribution to journal › Article › peer-review

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