Recombinant interferon alfa 2a in hepatic hemangiomatosis with congestive heart failure: A case report

Amalia Schiavetti; M. D. De Pasquale; S. Di Salvo; F. Ventriglia; A. Clerico

doi:10.1080/0880010390158676

Recombinant interferon alfa 2a in hepatic hemangiomatosis with congestive heart failure: A case report

Amalia Schiavetti, M. D. De Pasquale, S. Di Salvo, F. Ventriglia, A. Clerico

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

A 45-day-old patient was admitted with dyspnea, hepatomegaly, tachycardia, holosystolic murmur in the precordial region, and continuous murmur at the right hypochondrium. Four cutaneous angiomas were noted. Instrumental examinations revealed congestive heart failure and multipfocal lesions in the liver with typical features of hemangiomas. The therapy with subcutaneous interferon-alfa-2a (INF-α) was administered for 12 months with progressive regression of cutaneous hemangiomas, liver lesions, and cardiological alterations. IFN-α therapy was effective without any significant adverse effects.

Original language	English
Pages (from-to)	161-165
Number of pages	5
Journal	Pediatric Hematology and Oncology
Volume	20
Issue number	2
DOIs	https://doi.org/10.1080/0880010390158676
Publication status	Published - Mar 2003

Keywords

Congestive heart failure
Hepatic hemangiomatosis
Interferon-α-2a

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology
Cancer Research
Management of Technology and Innovation

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10.1080/0880010390158676

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abstract = "A 45-day-old patient was admitted with dyspnea, hepatomegaly, tachycardia, holosystolic murmur in the precordial region, and continuous murmur at the right hypochondrium. Four cutaneous angiomas were noted. Instrumental examinations revealed congestive heart failure and multipfocal lesions in the liver with typical features of hemangiomas. The therapy with subcutaneous interferon-alfa-2a (INF-α) was administered for 12 months with progressive regression of cutaneous hemangiomas, liver lesions, and cardiological alterations. IFN-α therapy was effective without any significant adverse effects.",

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AU - De Pasquale, M. D.

AU - Di Salvo, S.

AU - Ventriglia, F.

AU - Clerico, A.

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AB - A 45-day-old patient was admitted with dyspnea, hepatomegaly, tachycardia, holosystolic murmur in the precordial region, and continuous murmur at the right hypochondrium. Four cutaneous angiomas were noted. Instrumental examinations revealed congestive heart failure and multipfocal lesions in the liver with typical features of hemangiomas. The therapy with subcutaneous interferon-alfa-2a (INF-α) was administered for 12 months with progressive regression of cutaneous hemangiomas, liver lesions, and cardiological alterations. IFN-α therapy was effective without any significant adverse effects.

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KW - Hepatic hemangiomatosis

KW - Interferon-α-2a

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Recombinant interferon alfa 2a in hepatic hemangiomatosis with congestive heart failure: A case report

Abstract

Keywords

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