Abstract
This document describes the recommendations of a group of scientific societies concerning the first-line therapeutic approach to paediatric tuberculosis (TB). The treatment of pulmonary TB should be based on the existence of parenchymal involvement and the risk of antibiotic resistance. The treatment of extra-pulmonary TB is based on the regimens used for severe pulmonary TB. The administration of corticosteroids is recommended only in cases of miliary TB, tuberculous meningitis and tuberculous pericarditis. Vitamin B6 may be indicated in the case of isoniazid-treated TB in breastfeeding infants, severely malnourished subjects, or patients with other diseases at high risk of vitamin deficiency. Once having started treatment, children with TB should be carefully followed up in order to evaluate compliance, the response to treatment, the need for treatment changes, and the presence of drug-related adverse events. Primary care paediatricians can support reference centres in providing family healthcare education and encouraging treatment compliance.
| Original language | English |
|---|---|
| Pages (from-to) | 13-23 |
| Number of pages | 11 |
| Journal | Pediatric Drugs |
| Volume | 18 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2016 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Pharmacology (medical)
Cite this
Recommendations Concerning the First-Line Treatment of Children with Tuberculosis. / Principi, Nicola; Galli, Luisa; Lancella, Laura; Tadolini, Marina; Migliori, Giovanni Battista; Villani, Alberto; Esposito, Susanna; For The Italian Pediatric Tb Study Group, The Italian Pediatric Tb Study Group.
In: Pediatric Drugs, Vol. 18, No. 1, 2016, p. 13-23.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recommendations Concerning the First-Line Treatment of Children with Tuberculosis
AU - Principi, Nicola
AU - Galli, Luisa
AU - Lancella, Laura
AU - Tadolini, Marina
AU - Migliori, Giovanni Battista
AU - Villani, Alberto
AU - Esposito, Susanna
AU - For The Italian Pediatric Tb Study Group, The Italian Pediatric Tb Study Group
PY - 2016
Y1 - 2016
N2 - This document describes the recommendations of a group of scientific societies concerning the first-line therapeutic approach to paediatric tuberculosis (TB). The treatment of pulmonary TB should be based on the existence of parenchymal involvement and the risk of antibiotic resistance. The treatment of extra-pulmonary TB is based on the regimens used for severe pulmonary TB. The administration of corticosteroids is recommended only in cases of miliary TB, tuberculous meningitis and tuberculous pericarditis. Vitamin B6 may be indicated in the case of isoniazid-treated TB in breastfeeding infants, severely malnourished subjects, or patients with other diseases at high risk of vitamin deficiency. Once having started treatment, children with TB should be carefully followed up in order to evaluate compliance, the response to treatment, the need for treatment changes, and the presence of drug-related adverse events. Primary care paediatricians can support reference centres in providing family healthcare education and encouraging treatment compliance.
AB - This document describes the recommendations of a group of scientific societies concerning the first-line therapeutic approach to paediatric tuberculosis (TB). The treatment of pulmonary TB should be based on the existence of parenchymal involvement and the risk of antibiotic resistance. The treatment of extra-pulmonary TB is based on the regimens used for severe pulmonary TB. The administration of corticosteroids is recommended only in cases of miliary TB, tuberculous meningitis and tuberculous pericarditis. Vitamin B6 may be indicated in the case of isoniazid-treated TB in breastfeeding infants, severely malnourished subjects, or patients with other diseases at high risk of vitamin deficiency. Once having started treatment, children with TB should be carefully followed up in order to evaluate compliance, the response to treatment, the need for treatment changes, and the presence of drug-related adverse events. Primary care paediatricians can support reference centres in providing family healthcare education and encouraging treatment compliance.
UR - http://www.scopus.com/inward/record.url?scp=84948440713&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948440713&partnerID=8YFLogxK
U2 - 10.1007/s40272-015-0155-z
DO - 10.1007/s40272-015-0155-z
M3 - Article
C2 - 26612773
AN - SCOPUS:84948440713
VL - 18
SP - 13
EP - 23
JO - Paediatric Drugs
JF - Paediatric Drugs
SN - 1174-5878
IS - 1
ER -